Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications
The number of individuals suffering from fatty liver is increasing worldwide, leading to interest in the noninvasive study of liver fat. Magnetic resonance spectroscopy (MRS) is a powerful tool that allows direct quantification of metabolites in tissue or areas of interest. MRS has been applied in b...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/5/842 |
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| author | Duanghathai Pasanta Khin Thandar Htun Jie Pan Montree Tungjai Siriprapa Kaewjaeng Hongjoo Kim Jakrapong Kaewkhao Suchart Kothan |
| author_facet | Duanghathai Pasanta Khin Thandar Htun Jie Pan Montree Tungjai Siriprapa Kaewjaeng Hongjoo Kim Jakrapong Kaewkhao Suchart Kothan |
| author_sort | Duanghathai Pasanta |
| collection | DOAJ |
| description | The number of individuals suffering from fatty liver is increasing worldwide, leading to interest in the noninvasive study of liver fat. Magnetic resonance spectroscopy (MRS) is a powerful tool that allows direct quantification of metabolites in tissue or areas of interest. MRS has been applied in both research and clinical studies to assess liver fat noninvasively in vivo. MRS has also demonstrated excellent performance in liver fat assessment with high sensitivity and specificity compared to biopsy and other imaging modalities. Because of these qualities, MRS has been generally accepted as the reference standard for the noninvasive measurement of liver steatosis. MRS is an evolving technique with high potential as a diagnostic tool in the clinical setting. This review aims to provide a brief overview of the MRS principle for liver fat assessment and its application, and to summarize the current state of MRS study in comparison to other techniques. |
| first_indexed | 2024-03-10T11:37:31Z |
| format | Article |
| id | doaj.art-65db7e693e1942e3b80b3e683e976985 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T11:37:31Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-65db7e693e1942e3b80b3e683e9769852023-11-21T18:44:07ZengMDPI AGDiagnostics2075-44182021-05-0111584210.3390/diagnostics11050842Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical ApplicationsDuanghathai Pasanta0Khin Thandar Htun1Jie Pan2Montree Tungjai3Siriprapa Kaewjaeng4Hongjoo Kim5Jakrapong Kaewkhao6Suchart Kothan7Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, ThailandCenter of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, ThailandCenter of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, ThailandCenter of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, ThailandCenter of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Physics, Kyungpook National University, Daegu 41566, KoreaCenter of Excellence in Glass Technology and Materials Science (CEGM), Nakhon Pathom Rajabhat University, Nakhon Pathom 73000, ThailandCenter of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, ThailandThe number of individuals suffering from fatty liver is increasing worldwide, leading to interest in the noninvasive study of liver fat. Magnetic resonance spectroscopy (MRS) is a powerful tool that allows direct quantification of metabolites in tissue or areas of interest. MRS has been applied in both research and clinical studies to assess liver fat noninvasively in vivo. MRS has also demonstrated excellent performance in liver fat assessment with high sensitivity and specificity compared to biopsy and other imaging modalities. Because of these qualities, MRS has been generally accepted as the reference standard for the noninvasive measurement of liver steatosis. MRS is an evolving technique with high potential as a diagnostic tool in the clinical setting. This review aims to provide a brief overview of the MRS principle for liver fat assessment and its application, and to summarize the current state of MRS study in comparison to other techniques.https://www.mdpi.com/2075-4418/11/5/842magnetic resonance spectroscopyliver fathepatic steatosisliver fat fraction1H-MRS |
| spellingShingle | Duanghathai Pasanta Khin Thandar Htun Jie Pan Montree Tungjai Siriprapa Kaewjaeng Hongjoo Kim Jakrapong Kaewkhao Suchart Kothan Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications Diagnostics magnetic resonance spectroscopy liver fat hepatic steatosis liver fat fraction 1H-MRS |
| title | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
| title_full | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
| title_fullStr | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
| title_full_unstemmed | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
| title_short | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
| title_sort | magnetic resonance spectroscopy of hepatic fat from fundamental to clinical applications |
| topic | magnetic resonance spectroscopy liver fat hepatic steatosis liver fat fraction 1H-MRS |
| url | https://www.mdpi.com/2075-4418/11/5/842 |
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