Endothelial Cell Adhesion Molecules- (un)Attainable Targets for Nanomedicines

Endothelial cell adhesion molecules have long been proposed as promising targets in many pathologies. Despite promising preclinical data, several efforts to develop small molecule inhibitors or monoclonal antibodies (mAbs) against cell adhesion molecules (CAMs) ended in clinical-stage failure. In pa...

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Bibliographic Details
Main Authors: Nenad Milošević, Marie Rütter, Ayelet David
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Medical Technology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmedt.2022.846065/full