Developing Pharmacological Therapies for Atrial Fibrillation Targeting Mitochondrial Dysfunction and Oxidative Stress: A Scoping Review

Developing Pharmacological Therapies for Atrial Fibrillation Targeting Mitochondrial Dysfunction and Oxidative Stress: A Scoping Review

Atrial fibrillation (AF) is a cardiac arrhythmia caused by electrophysiological anomalies in the atrial tissue, tissue degradation, structural abnormalities, and comorbidities. A direct relationship exists between AF and altered mitochondrial activity resulting from membrane potential loss, contract...

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Bibliographic Details
Main Authors: Antônio da Silva Menezes Júnior, Ana Luísa Guedes de França-e-Silva, Joyce Monteiro de Oliveira, Daniela Melo da Silva
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
atrial fibrillation
mitochondrial dysfunction
inflammation
antioxidant drug discovery
Online Access:https://www.mdpi.com/1422-0067/25/1/535

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