Ca2+‐activated Cl− channels (TMEM16A) underlie spontaneous electrical activity in isolated mouse corpus cavernosum smooth muscle cells

Ca2+‐activated Cl− channels (TMEM16A) underlie spontaneous electrical activity in isolated mouse corpus cavernosum smooth muscle cells

Abstract Penile detumescence is maintained by tonic contraction of corpus cavernosum smooth muscle cells (CCSMC), but the underlying mechanisms have not been fully elucidated. The purpose of this study was to characterize the mechanisms underlying activation of TMEM16A Ca2+‐activated Cl− channels in...

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Bibliographic Details
Main Authors: Xin Rui Lim, Bernard T. Drumm, Gerard P. Sergeant, Mark A. Hollywood, Keith D. Thornbury
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Physiological Reports
Subjects:
corpus cavernosum
patch clamp
smooth muscle
TMEM16A
Online Access:https://doi.org/10.14814/phy2.15504

Internet

https://doi.org/10.14814/phy2.15504

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