Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy?
A 16-year-old girl was referred as retinitis and vasculitis post-typhoid fever. Fundus examination revealed bilateral pseudo-sheathing, scattered hemorrhages with retinal infiltrates. Wide-field fundus fluorescein angiography (FFA) showed peripheral vascular hyperfluorescence; 55° FFA images showed...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=2017;epage=2019;aulast=Kawali |
| _version_ | 1818942580633632768 |
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| author | Ankush Kawali Padmamalini Mahendradas Sanjay Srinivasan Rohit Shetty |
| author_facet | Ankush Kawali Padmamalini Mahendradas Sanjay Srinivasan Rohit Shetty |
| author_sort | Ankush Kawali |
| collection | DOAJ |
| description | A 16-year-old girl was referred as retinitis and vasculitis post-typhoid fever. Fundus examination revealed bilateral pseudo-sheathing, scattered hemorrhages with retinal infiltrates. Wide-field fundus fluorescein angiography (FFA) showed peripheral vascular hyperfluorescence; 55° FFA images showed a “firecracker-like” peripheral vasculature, but a closer look revealed miliary microaneurysms (MAs). Peripheral smear examination clinched the diagnosis of chronic myeloid leukemia. MAs on FFA in leukemic retinopathy have been frequently described in the literature. Our report emphasizes its presence, miliary nature, and need for closer inspection of FFA images. We believe that this angiographic sign has potential to become one of the imaging biomarkers of leukemic retinopathy. |
| first_indexed | 2024-12-20T07:13:42Z |
| format | Article |
| id | doaj.art-65e2bdc169a144dc8cfdb42b87099c04 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-20T07:13:42Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-65e2bdc169a144dc8cfdb42b87099c042022-12-21T19:48:50ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-016892017201910.4103/ijo.IJO_2375_19Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy?Ankush KawaliPadmamalini MahendradasSanjay SrinivasanRohit ShettyA 16-year-old girl was referred as retinitis and vasculitis post-typhoid fever. Fundus examination revealed bilateral pseudo-sheathing, scattered hemorrhages with retinal infiltrates. Wide-field fundus fluorescein angiography (FFA) showed peripheral vascular hyperfluorescence; 55° FFA images showed a “firecracker-like” peripheral vasculature, but a closer look revealed miliary microaneurysms (MAs). Peripheral smear examination clinched the diagnosis of chronic myeloid leukemia. MAs on FFA in leukemic retinopathy have been frequently described in the literature. Our report emphasizes its presence, miliary nature, and need for closer inspection of FFA images. We believe that this angiographic sign has potential to become one of the imaging biomarkers of leukemic retinopathy.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=2017;epage=2019;aulast=Kawalicmlfluorescein angiographyleukemialeukemic retinopathymiliary microaneurysm |
| spellingShingle | Ankush Kawali Padmamalini Mahendradas Sanjay Srinivasan Rohit Shetty Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy? Indian Journal of Ophthalmology cml fluorescein angiography leukemia leukemic retinopathy miliary microaneurysm |
| title | Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy? |
| title_full | Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy? |
| title_fullStr | Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy? |
| title_full_unstemmed | Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy? |
| title_short | Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy? |
| title_sort | miliary microaneurysms an angiographic biomarker of leukemic retinopathy |
| topic | cml fluorescein angiography leukemia leukemic retinopathy miliary microaneurysm |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=2017;epage=2019;aulast=Kawali |
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