[Fever of Unknown Origin in a Patient Administered With Bacillus Calmette-Guérin (BCG) to Treat Urothelial Vesical Carcinoma in Situ]
Koch’s Bacillus bovis (Mycobacterium bovis) was made avirulent by special culture conditions, i.e., 230 passages on medium containing potatoes treated with bile salts. It has been used mainly to prevent tuberculosis. The vaccine was named after the bacteriologist Albert Calmette and the veterinarian...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SEEd
2023-07-01
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| Series: | Clinical Management Issues |
| Subjects: | |
| Online Access: | http://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1543 |
| _version_ | 1827898344469430272 |
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| author | Paolo Ghiringhelli Federica Macchi Mariella Ciola Girolamo Sala Beatrice Valvo Andrea Agostinelli Lorenzo Bellintani Gaetano Emanuele Rizzo Michela Provisione Michela Zaza Alessandro Diana Maurizio Ferrarese |
| author_facet | Paolo Ghiringhelli Federica Macchi Mariella Ciola Girolamo Sala Beatrice Valvo Andrea Agostinelli Lorenzo Bellintani Gaetano Emanuele Rizzo Michela Provisione Michela Zaza Alessandro Diana Maurizio Ferrarese |
| author_sort | Paolo Ghiringhelli |
| collection | DOAJ |
| description | Koch’s Bacillus bovis (Mycobacterium bovis) was made avirulent by special culture conditions, i.e., 230 passages on medium containing potatoes treated with bile salts. It has been used mainly to prevent tuberculosis. The vaccine was named after the bacteriologist Albert Calmette and the veterinarian Camille Guérin, i.e., Bacillus Calmette-Guérin (BCG). These researchers worked at the Pasteur Institute in Lille and launched the vaccine in 1921.
Recently, BCG was used also for its non-specific immunostimulant action. Intravesical administration of BCG is an adjunctive therapy for the treatment of bladder cancer, which does not invade the muscle wall.
We will discuss the clinical case of a patient who had fever of unknown origin for about 2 months and was resistant to treatment with multiple lines of antibiotics. |
| first_indexed | 2024-03-12T23:01:45Z |
| format | Article |
| id | doaj.art-65e3495270d44228bcf569287a25b445 |
| institution | Directory Open Access Journal |
| issn | 2283-3137 |
| language | English |
| last_indexed | 2024-03-12T23:01:45Z |
| publishDate | 2023-07-01 |
| publisher | SEEd |
| record_format | Article |
| series | Clinical Management Issues |
| spelling | doaj.art-65e3495270d44228bcf569287a25b4452023-07-19T09:18:48ZengSEEdClinical Management Issues2283-31372023-07-0117110.7175/cmi.v17i1.15431360[Fever of Unknown Origin in a Patient Administered With Bacillus Calmette-Guérin (BCG) to Treat Urothelial Vesical Carcinoma in Situ]Paolo Ghiringhelli0Federica Macchi1Mariella Ciola2Girolamo Sala3Beatrice Valvo4Andrea Agostinelli5Lorenzo Bellintani6Gaetano Emanuele Rizzo7Michela Provisione8Michela Zaza9Alessandro Diana10Maurizio Ferrarese11Medicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaMedicina Interna Ospedale di Busto Arsizio, ASST Valle Olona, ItaliaTisiologia, Ospedale di Niguarda, Milano, ItaliaKoch’s Bacillus bovis (Mycobacterium bovis) was made avirulent by special culture conditions, i.e., 230 passages on medium containing potatoes treated with bile salts. It has been used mainly to prevent tuberculosis. The vaccine was named after the bacteriologist Albert Calmette and the veterinarian Camille Guérin, i.e., Bacillus Calmette-Guérin (BCG). These researchers worked at the Pasteur Institute in Lille and launched the vaccine in 1921. Recently, BCG was used also for its non-specific immunostimulant action. Intravesical administration of BCG is an adjunctive therapy for the treatment of bladder cancer, which does not invade the muscle wall. We will discuss the clinical case of a patient who had fever of unknown origin for about 2 months and was resistant to treatment with multiple lines of antibiotics.http://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1543bcgurothelial carcinomafevermycobacterium bovis |
| spellingShingle | Paolo Ghiringhelli Federica Macchi Mariella Ciola Girolamo Sala Beatrice Valvo Andrea Agostinelli Lorenzo Bellintani Gaetano Emanuele Rizzo Michela Provisione Michela Zaza Alessandro Diana Maurizio Ferrarese [Fever of Unknown Origin in a Patient Administered With Bacillus Calmette-Guérin (BCG) to Treat Urothelial Vesical Carcinoma in Situ] Clinical Management Issues bcg urothelial carcinoma fever mycobacterium bovis |
| title | [Fever of Unknown Origin in a Patient Administered With Bacillus Calmette-Guérin (BCG) to Treat Urothelial Vesical Carcinoma in Situ] |
| title_full | [Fever of Unknown Origin in a Patient Administered With Bacillus Calmette-Guérin (BCG) to Treat Urothelial Vesical Carcinoma in Situ] |
| title_fullStr | [Fever of Unknown Origin in a Patient Administered With Bacillus Calmette-Guérin (BCG) to Treat Urothelial Vesical Carcinoma in Situ] |
| title_full_unstemmed | [Fever of Unknown Origin in a Patient Administered With Bacillus Calmette-Guérin (BCG) to Treat Urothelial Vesical Carcinoma in Situ] |
| title_short | [Fever of Unknown Origin in a Patient Administered With Bacillus Calmette-Guérin (BCG) to Treat Urothelial Vesical Carcinoma in Situ] |
| title_sort | fever of unknown origin in a patient administered with bacillus calmette guerin bcg to treat urothelial vesical carcinoma in situ |
| topic | bcg urothelial carcinoma fever mycobacterium bovis |
| url | http://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1543 |
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