On-line aptamer affinity solid-phase extraction capillary electrophoresis-mass spectrometry for the analysis of protein biomarkers in biological fluids and food: A tutorial

The analysis by capillary electrophoresis (CE) of low abundant proteins in complex samples, such as biological fluids and food, is especially challenging, due to the poor concentration sensitivity of microscale separation techniques and the sample matrix complexity. In order to overcome these major...

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Bibliographic Details
Main Authors: María Vergara-Barberán, Laura Pont, Hiba Salim, Estela Giménez, Fernando Benavente
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Advances in Sample Preparation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772582023000323