Progress and prospects of nanocomposite hydrogels in bone tissue engineering
Hydrogels are hydrophilic polymers with high flexibility and elasticity, and are widely used in the field of bone tissue engineering. However, their low toughness and insufficient mechanical strength have limited their applications. Nanocomposite hydrogels are flexible and porous as well as possess...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-05-01
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| Series: | Nanocomposites |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/20550324.2022.2076025 |
| _version_ | 1818204092683517952 |
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| author | Chengcheng Du Wei Huang |
| author_facet | Chengcheng Du Wei Huang |
| author_sort | Chengcheng Du |
| collection | DOAJ |
| description | Hydrogels are hydrophilic polymers with high flexibility and elasticity, and are widely used in the field of bone tissue engineering. However, their low toughness and insufficient mechanical strength have limited their applications. Nanocomposite hydrogels are flexible and porous as well as possess excellent biocompatibility and mechanical strength, thus exhibiting a significant potential to be used in the field of bone tissue engineering. Nanocomposite hydrogels are synthesized by chemically or physically crosslinking nanomaterials and hydrogels, and their physical, chemical, and biological properties can be enhanced by changing the properties and compositions of the nanomaterials. Both nanomaterials and hydrogel polymers can be customized, and therefore, nanocomposite hydrogels can be developed for bone repair under different conditions. In this review, we first introduce the synthesis methods and properties of nanocomposite hydrogels, and then summarize the applications and progress of nanocomposite hydrogels in bone tissue engineering. |
| first_indexed | 2024-12-12T03:35:45Z |
| format | Article |
| id | doaj.art-65e6655c482b4814b806f25b555f5a91 |
| institution | Directory Open Access Journal |
| issn | 2055-0324 2055-0332 |
| language | English |
| last_indexed | 2024-12-12T03:35:45Z |
| publishDate | 2022-05-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Nanocomposites |
| spelling | doaj.art-65e6655c482b4814b806f25b555f5a912022-12-22T00:39:49ZengTaylor & Francis GroupNanocomposites2055-03242055-03322022-05-018110212410.1080/20550324.2022.2076025Progress and prospects of nanocomposite hydrogels in bone tissue engineeringChengcheng Du0Wei Huang1Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Orthopaedic Laboratory of Chongqing Medical University, Chongqing, ChinaDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Orthopaedic Laboratory of Chongqing Medical University, Chongqing, ChinaHydrogels are hydrophilic polymers with high flexibility and elasticity, and are widely used in the field of bone tissue engineering. However, their low toughness and insufficient mechanical strength have limited their applications. Nanocomposite hydrogels are flexible and porous as well as possess excellent biocompatibility and mechanical strength, thus exhibiting a significant potential to be used in the field of bone tissue engineering. Nanocomposite hydrogels are synthesized by chemically or physically crosslinking nanomaterials and hydrogels, and their physical, chemical, and biological properties can be enhanced by changing the properties and compositions of the nanomaterials. Both nanomaterials and hydrogel polymers can be customized, and therefore, nanocomposite hydrogels can be developed for bone repair under different conditions. In this review, we first introduce the synthesis methods and properties of nanocomposite hydrogels, and then summarize the applications and progress of nanocomposite hydrogels in bone tissue engineering.https://www.tandfonline.com/doi/10.1080/20550324.2022.2076025Nanoparticlesnanocomposite hydrogelbone tissue engineering |
| spellingShingle | Chengcheng Du Wei Huang Progress and prospects of nanocomposite hydrogels in bone tissue engineering Nanocomposites Nanoparticles nanocomposite hydrogel bone tissue engineering |
| title | Progress and prospects of nanocomposite hydrogels in bone tissue engineering |
| title_full | Progress and prospects of nanocomposite hydrogels in bone tissue engineering |
| title_fullStr | Progress and prospects of nanocomposite hydrogels in bone tissue engineering |
| title_full_unstemmed | Progress and prospects of nanocomposite hydrogels in bone tissue engineering |
| title_short | Progress and prospects of nanocomposite hydrogels in bone tissue engineering |
| title_sort | progress and prospects of nanocomposite hydrogels in bone tissue engineering |
| topic | Nanoparticles nanocomposite hydrogel bone tissue engineering |
| url | https://www.tandfonline.com/doi/10.1080/20550324.2022.2076025 |
| work_keys_str_mv | AT chengchengdu progressandprospectsofnanocompositehydrogelsinbonetissueengineering AT weihuang progressandprospectsofnanocompositehydrogelsinbonetissueengineering |