Anti-Ischemic Effect of Leptin in the Isolated Rat Heart Subjected to Global Ischemia-Reperfusion: Role of Cardiac-Specific miRNAs

Anti-Ischemic Effect of Leptin in the Isolated Rat Heart Subjected to Global Ischemia-Reperfusion: Role of Cardiac-Specific miRNAs

Background: Leptin is an obesity-associated adipokine that has been implicated in cardiac protection against ischemia-reperfusion injury (IRI). In this study, concentration-dependent effects of leptin on myocardial IRI were investigated in the isolated rat heart. In addition, we analyzed myocardial...

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Bibliographic Details
Main Authors: Ekaterina A. Polyakova, Evgeny N. Mikhaylov, Sarkis M. Minasian, Mikhail M. Galagudza, Evgeny V. Shlyakhto
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cardiogenetics
Subjects:
leptin
heart
ischemia
reperfusion
infarct size
rat
Online Access:https://www.mdpi.com/2035-8148/13/1/1

Internet

https://www.mdpi.com/2035-8148/13/1/1

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