Increased oxidative stress caused by impaired mitophagy aggravated liver ischemia and reperfusion injury in diabetic mice

Abstract Aims/Introduction Emerging evidence has suggested the detrimental role of oxidative stress in aggravating ischemia and reperfusion (IR) injury in diabetic livers. Interplay between oxidative stress and mitophagy has been shown. However, the role and mechanism of mitophagy in regulating oxid...

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Bibliographic Details
Main Authors: Kong Zhijun, Zhang Xudong, Wu Baoqiang, Zhu Chunfu, Yu Qiang, Gao Yuan, Qin Xihu
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Diabetes Investigation
Subjects:
Online Access:https://doi.org/10.1111/jdi.13928