Experimental study of Otitis media with Pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and Lactobacillus acidophilus

This study has revealed the importance of natural herbal products to control antibiotics resistant bacteria which are being a threat to human and animal health and focused on antibacterial potential of aqueous infusion of Dandelion alcoholic cold extract against Pseudomonas aeruginosa. The exper...

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Main Author: Narjis A. Al-khafaji
Format: Article
Language:English
Published: University of Baghdad, College of Veterinary Medicine 2013-12-01
Series:The Iraqi Journal of Veterinary Medicine
Subjects:
Online Access:https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1394
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author Narjis A. Al-khafaji
author_facet Narjis A. Al-khafaji
author_sort Narjis A. Al-khafaji
collection DOAJ
description This study has revealed the importance of natural herbal products to control antibiotics resistant bacteria which are being a threat to human and animal health and focused on antibacterial potential of aqueous infusion of Dandelion alcoholic cold extract against Pseudomonas aeruginosa. The experimental studies include (18) healthy mice were randomly divided in to 6 equal groups, all 5th group injected with P. aerugenosa 106CFU/ ml (0.05 ml) except 6th group which injected with phosphate buffer saline (control negative). 1st group killed after 48hr of injection, 2nd group treated with otucalm, 3 rd treated with Dandelion cold alcoholic extract, 4 th group treated with Dandelion locally and lactobacillus acidophilus orally, 5 th group injected with bacteria (control positive) and killed after the end of the experiment. The result showed that the 4th group was the best group show the highly sensitive effect in vitro and no clear pathological lesion and increase the immunity and health of animal in vivo compare with other groups. Dandelion showed nontoxic effect and noncombination with other drugs and significantly increased the ability of P. aerugenosa isolated from otitis media it’s more pathogenic than bacteria isolated from others organs in the same animals.
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spelling doaj.art-65eaf72de5024deda3f7dd87c518ad882023-01-07T03:03:21ZengUniversity of Baghdad, College of Veterinary MedicineThe Iraqi Journal of Veterinary Medicine1609-56932410-74092013-12-0137210.30539/ijvm.v37i2.1394Experimental study of Otitis media with Pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and Lactobacillus acidophilusNarjis A. Al-khafaji0Zoonotic disease unit, College of Veterinary Medicine, Baghdad University, Iraq This study has revealed the importance of natural herbal products to control antibiotics resistant bacteria which are being a threat to human and animal health and focused on antibacterial potential of aqueous infusion of Dandelion alcoholic cold extract against Pseudomonas aeruginosa. The experimental studies include (18) healthy mice were randomly divided in to 6 equal groups, all 5th group injected with P. aerugenosa 106CFU/ ml (0.05 ml) except 6th group which injected with phosphate buffer saline (control negative). 1st group killed after 48hr of injection, 2nd group treated with otucalm, 3 rd treated with Dandelion cold alcoholic extract, 4 th group treated with Dandelion locally and lactobacillus acidophilus orally, 5 th group injected with bacteria (control positive) and killed after the end of the experiment. The result showed that the 4th group was the best group show the highly sensitive effect in vitro and no clear pathological lesion and increase the immunity and health of animal in vivo compare with other groups. Dandelion showed nontoxic effect and noncombination with other drugs and significantly increased the ability of P. aerugenosa isolated from otitis media it’s more pathogenic than bacteria isolated from others organs in the same animals. https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1394Otitis mediaDandelionOtucalmP. aeuginosa
spellingShingle Narjis A. Al-khafaji
Experimental study of Otitis media with Pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and Lactobacillus acidophilus
The Iraqi Journal of Veterinary Medicine
Otitis media
Dandelion
Otucalm
P. aeuginosa
title Experimental study of Otitis media with Pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and Lactobacillus acidophilus
title_full Experimental study of Otitis media with Pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and Lactobacillus acidophilus
title_fullStr Experimental study of Otitis media with Pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and Lactobacillus acidophilus
title_full_unstemmed Experimental study of Otitis media with Pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and Lactobacillus acidophilus
title_short Experimental study of Otitis media with Pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and Lactobacillus acidophilus
title_sort experimental study of otitis media with pseudomonas aerugenonsa in mice and treated with alcoholic cold extract of dandelion compared with used of otucalm drops and lactobacillus acidophilus
topic Otitis media
Dandelion
Otucalm
P. aeuginosa
url https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1394
work_keys_str_mv AT narjisaalkhafaji experimentalstudyofotitismediawithpseudomonasaerugenonsainmiceandtreatedwithalcoholiccoldextractofdandelioncomparedwithusedofotucalmdropsandlactobacillusacidophilus