Metabolic changes of Interleukin-12/15/18-stimulated human NK cells

Abstract Natural Killer (NK) cells acquire memory-like properties following a brief stimulation with IL-12, IL-15 and IL-18. These IL-12/15/18-preactivated NK cells, also known as cytokine-induced memory-like (CIML) NK cells, have been revealed as a powerful tool in cancer immunotherapy due to their...

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Bibliographic Details
Main Authors: Iñigo Terrén, Ane Orrantia, Alba Mosteiro, Joana Vitallé, Olatz Zenarruzabeitia, Francisco Borrego
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85960-6