Interferon-α-Induced Dendritic Cells Generated with Human Platelet Lysate Exhibit Elevated Antigen Presenting Ability to Cytotoxic T Lymphocytes

Interferon-α-Induced Dendritic Cells Generated with Human Platelet Lysate Exhibit Elevated Antigen Presenting Ability to Cytotoxic T Lymphocytes

Given the recent advancements of immune checkpoint inhibitors, there is considerable interest in cancer immunotherapy provided through dendritic cell (DC)-based vaccination. Although many studies have been conducted to determine the potency of DC vaccines against cancer, the clinical outcomes are no...

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Bibliographic Details
Main Authors: Ippei Date, Terutsugu Koya, Takuya Sakamoto, Misa Togi, Haruhiko Kawaguchi, Asuka Watanabe, Tomohisa Kato, Shigetaka Shimodaira
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Vaccines
Subjects:
immunotherapy
dendritic cells
vaccine
human platelet lysate
tumor-associated antigens
cytotoxic T lymphocyte
Online Access:https://www.mdpi.com/2076-393X/9/1/10

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