The effect of Qatada (Acacia hamulosa) honey from Saudi Arabia on the steps of pilonidal sinus healing
The purpose of this study was to provide more light on the effect of Qatada (Acacia hamulosa) honey from Saudi Arabia as a dressing on pilonidal sinus wound healing, antibacterial activity, and cytokine levels. The results revealed that the pH of 3.56 of tested honey, where glucose was 378 mmol/l al...
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| Format: | Article |
| Language: | English |
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International Library of Sciences
2021-11-01
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| Series: | Highlights in BioScience |
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| Online Access: | http://highlightsin.org/index.php/bioscience/article/view/91 |
| _version_ | 1811258597414273024 |
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| author | Ahmed G. Hegazi Faiz M. Al Guthami Mohamed H. Basiouny Ahmed F.M. Al Gethami |
| author_facet | Ahmed G. Hegazi Faiz M. Al Guthami Mohamed H. Basiouny Ahmed F.M. Al Gethami |
| author_sort | Ahmed G. Hegazi |
| collection | DOAJ |
| description | The purpose of this study was to provide more light on the effect of Qatada (Acacia hamulosa) honey from Saudi Arabia as a dressing on pilonidal sinus wound healing, antibacterial activity, and cytokine levels. The results revealed that the pH of 3.56 of tested honey, where glucose was 378 mmol/l also the specific gravity was 1.435, while contents of total phenolic and flavonoid and DPPH activity (32.15 mg GAE/100 g honey), (54.27 mg RE/100 g honey) and (127.83 mg/ml) respectively. The mean duration of pilonidal sinus wounds to be ready for surgical closure was 43.5 days in the control (standard dressing) group where the honey dressing group was 28.5 days. Less pain, edema, and foul-smelling discharge were expressed in the honey group if compared with the standard dressing group. The total bacterial count was 9 × 109 at the begging of the experiment then it reduced after the application of standard dressing traditional therapy to (9 ×105) and honey treatment group (9 ×102) after 21 days post-treatment. Significant reduction (p0.05) was observed in serum TNFα(-52), IL6 - 46), and IL-17 (-60) relatively to pre-treatment values. Based on our findings, we may conclude that Qatada honey bioactivities aided wound healing by increasing tissue growth while decreasing overall bacterial count and inflammation. |
| first_indexed | 2024-04-12T18:16:50Z |
| format | Article |
| id | doaj.art-65f341378213479b8645d90ef3968a51 |
| institution | Directory Open Access Journal |
| issn | 2682-4043 |
| language | English |
| last_indexed | 2024-04-12T18:16:50Z |
| publishDate | 2021-11-01 |
| publisher | International Library of Sciences |
| record_format | Article |
| series | Highlights in BioScience |
| spelling | doaj.art-65f341378213479b8645d90ef3968a512022-12-22T03:21:34ZengInternational Library of SciencesHighlights in BioScience2682-40432021-11-014010.36462/H.BioSci.20211051The effect of Qatada (Acacia hamulosa) honey from Saudi Arabia on the steps of pilonidal sinus healingAhmed G. Hegazi0Faiz M. Al Guthami1Mohamed H. Basiouny2Ahmed F.M. Al Gethami3National Research Centre, Dokki, GizaAl Guthami Foundation,Ministry of HealthAl Guthami FoundationThe purpose of this study was to provide more light on the effect of Qatada (Acacia hamulosa) honey from Saudi Arabia as a dressing on pilonidal sinus wound healing, antibacterial activity, and cytokine levels. The results revealed that the pH of 3.56 of tested honey, where glucose was 378 mmol/l also the specific gravity was 1.435, while contents of total phenolic and flavonoid and DPPH activity (32.15 mg GAE/100 g honey), (54.27 mg RE/100 g honey) and (127.83 mg/ml) respectively. The mean duration of pilonidal sinus wounds to be ready for surgical closure was 43.5 days in the control (standard dressing) group where the honey dressing group was 28.5 days. Less pain, edema, and foul-smelling discharge were expressed in the honey group if compared with the standard dressing group. The total bacterial count was 9 × 109 at the begging of the experiment then it reduced after the application of standard dressing traditional therapy to (9 ×105) and honey treatment group (9 ×102) after 21 days post-treatment. Significant reduction (p0.05) was observed in serum TNFα(-52), IL6 - 46), and IL-17 (-60) relatively to pre-treatment values. Based on our findings, we may conclude that Qatada honey bioactivities aided wound healing by increasing tissue growth while decreasing overall bacterial count and inflammation.http://highlightsin.org/index.php/bioscience/article/view/91antibacterial activity, cytokines, pilonidal sinus, honey, healing |
| spellingShingle | Ahmed G. Hegazi Faiz M. Al Guthami Mohamed H. Basiouny Ahmed F.M. Al Gethami The effect of Qatada (Acacia hamulosa) honey from Saudi Arabia on the steps of pilonidal sinus healing Highlights in BioScience antibacterial activity, cytokines, pilonidal sinus, honey, healing |
| title | The effect of Qatada (Acacia hamulosa) honey from Saudi Arabia on the steps of pilonidal sinus healing |
| title_full | The effect of Qatada (Acacia hamulosa) honey from Saudi Arabia on the steps of pilonidal sinus healing |
| title_fullStr | The effect of Qatada (Acacia hamulosa) honey from Saudi Arabia on the steps of pilonidal sinus healing |
| title_full_unstemmed | The effect of Qatada (Acacia hamulosa) honey from Saudi Arabia on the steps of pilonidal sinus healing |
| title_short | The effect of Qatada (Acacia hamulosa) honey from Saudi Arabia on the steps of pilonidal sinus healing |
| title_sort | effect of qatada acacia hamulosa honey from saudi arabia on the steps of pilonidal sinus healing |
| topic | antibacterial activity, cytokines, pilonidal sinus, honey, healing |
| url | http://highlightsin.org/index.php/bioscience/article/view/91 |
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