Mitochondrial homeostasis is maintained in the absence of autophagy
Autophagy is a central recycling process, and it plays a complex role in cancer. We discovered that when autophagy is blocked, cancer cells compensate by increasing mitochondrial-derived vesicles. However, there are many unanswered questions remaining, particularly in the context of the dual roles o...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2021-09-01
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Series: | Molecular & Cellular Oncology |
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Online Access: | http://dx.doi.org/10.1080/23723556.2021.1984162 |
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author | Christina G. Towers |
author_facet | Christina G. Towers |
author_sort | Christina G. Towers |
collection | DOAJ |
description | Autophagy is a central recycling process, and it plays a complex role in cancer. We discovered that when autophagy is blocked, cancer cells compensate by increasing mitochondrial-derived vesicles. However, there are many unanswered questions remaining, particularly in the context of the dual roles of autophagy in cancer. |
first_indexed | 2024-03-11T22:39:51Z |
format | Article |
id | doaj.art-65f90c24444247ae96cf657ed33320c8 |
institution | Directory Open Access Journal |
issn | 2372-3556 |
language | English |
last_indexed | 2024-03-11T22:39:51Z |
publishDate | 2021-09-01 |
publisher | Taylor & Francis Group |
record_format | Article |
series | Molecular & Cellular Oncology |
spelling | doaj.art-65f90c24444247ae96cf657ed33320c82023-09-22T09:19:43ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562021-09-018510.1080/23723556.2021.19841621984162Mitochondrial homeostasis is maintained in the absence of autophagyChristina G. Towers0The Salk Institute for Biological StudiesAutophagy is a central recycling process, and it plays a complex role in cancer. We discovered that when autophagy is blocked, cancer cells compensate by increasing mitochondrial-derived vesicles. However, there are many unanswered questions remaining, particularly in the context of the dual roles of autophagy in cancer.http://dx.doi.org/10.1080/23723556.2021.1984162autophagymitochondrial derived vesiclescancermitophagymitochondria |
spellingShingle | Christina G. Towers Mitochondrial homeostasis is maintained in the absence of autophagy Molecular & Cellular Oncology autophagy mitochondrial derived vesicles cancer mitophagy mitochondria |
title | Mitochondrial homeostasis is maintained in the absence of autophagy |
title_full | Mitochondrial homeostasis is maintained in the absence of autophagy |
title_fullStr | Mitochondrial homeostasis is maintained in the absence of autophagy |
title_full_unstemmed | Mitochondrial homeostasis is maintained in the absence of autophagy |
title_short | Mitochondrial homeostasis is maintained in the absence of autophagy |
title_sort | mitochondrial homeostasis is maintained in the absence of autophagy |
topic | autophagy mitochondrial derived vesicles cancer mitophagy mitochondria |
url | http://dx.doi.org/10.1080/23723556.2021.1984162 |
work_keys_str_mv | AT christinagtowers mitochondrialhomeostasisismaintainedintheabsenceofautophagy |