Mitochondrial homeostasis is maintained in the absence of autophagy

Autophagy is a central recycling process, and it plays a complex role in cancer. We discovered that when autophagy is blocked, cancer cells compensate by increasing mitochondrial-derived vesicles. However, there are many unanswered questions remaining, particularly in the context of the dual roles o...

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Main Author: Christina G. Towers
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2021.1984162
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author Christina G. Towers
author_facet Christina G. Towers
author_sort Christina G. Towers
collection DOAJ
description Autophagy is a central recycling process, and it plays a complex role in cancer. We discovered that when autophagy is blocked, cancer cells compensate by increasing mitochondrial-derived vesicles. However, there are many unanswered questions remaining, particularly in the context of the dual roles of autophagy in cancer.
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spelling doaj.art-65f90c24444247ae96cf657ed33320c82023-09-22T09:19:43ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562021-09-018510.1080/23723556.2021.19841621984162Mitochondrial homeostasis is maintained in the absence of autophagyChristina G. Towers0The Salk Institute for Biological StudiesAutophagy is a central recycling process, and it plays a complex role in cancer. We discovered that when autophagy is blocked, cancer cells compensate by increasing mitochondrial-derived vesicles. However, there are many unanswered questions remaining, particularly in the context of the dual roles of autophagy in cancer.http://dx.doi.org/10.1080/23723556.2021.1984162autophagymitochondrial derived vesiclescancermitophagymitochondria
spellingShingle Christina G. Towers
Mitochondrial homeostasis is maintained in the absence of autophagy
Molecular & Cellular Oncology
autophagy
mitochondrial derived vesicles
cancer
mitophagy
mitochondria
title Mitochondrial homeostasis is maintained in the absence of autophagy
title_full Mitochondrial homeostasis is maintained in the absence of autophagy
title_fullStr Mitochondrial homeostasis is maintained in the absence of autophagy
title_full_unstemmed Mitochondrial homeostasis is maintained in the absence of autophagy
title_short Mitochondrial homeostasis is maintained in the absence of autophagy
title_sort mitochondrial homeostasis is maintained in the absence of autophagy
topic autophagy
mitochondrial derived vesicles
cancer
mitophagy
mitochondria
url http://dx.doi.org/10.1080/23723556.2021.1984162
work_keys_str_mv AT christinagtowers mitochondrialhomeostasisismaintainedintheabsenceofautophagy