Metaplastic carcinoma with osteosarcomatous differentiation in the breast: Case report

Metaplastic breast carcinoma is rare and may present as a highly aggressive subtype of breast cancer. In this case report of metastatic metaplastic breast carcinoma with osteosarcomatous differentiation in a female patient previously treated for invasive ductal carcinoma, we describe the new present...

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Main Authors: Belinda Asare, MD, Marissa Janine White, MD, Joanna Rossi, MD, MPH
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Radiology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043323006209
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author Belinda Asare, MD
Marissa Janine White, MD
Joanna Rossi, MD, MPH
author_facet Belinda Asare, MD
Marissa Janine White, MD
Joanna Rossi, MD, MPH
author_sort Belinda Asare, MD
collection DOAJ
description Metaplastic breast carcinoma is rare and may present as a highly aggressive subtype of breast cancer. In this case report of metastatic metaplastic breast carcinoma with osteosarcomatous differentiation in a female patient previously treated for invasive ductal carcinoma, we describe the new presentation of a palpable mass with associated calcifications on imaging near the site of prior partial mastectomy. This article will detail the clinical presentation, imaging findings, histopathology, and clinical course following treatment of our case. Knowledge of the clinical and imaging presentation of this rare subtype, which can present with benign features on mammography and ultrasound, can facilitate timely diagnosis as treatment paradigms evolve.
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spelling doaj.art-6603806f4ac24af7abe9784a4a6168df2023-10-22T04:48:42ZengElsevierRadiology Case Reports1930-04332023-12-01181242724280Metaplastic carcinoma with osteosarcomatous differentiation in the breast: Case reportBelinda Asare, MD0Marissa Janine White, MD1Joanna Rossi, MD, MPH2Johns Hopkins University School of Medicine, 601 N. Caroline St, Baltimore, MD 21287, USAJohns Hopkins University School of Medicine, 601 N. Caroline St, Baltimore, MD 21287, USACorresponding author.; Johns Hopkins University School of Medicine, 601 N. Caroline St, Baltimore, MD 21287, USAMetaplastic breast carcinoma is rare and may present as a highly aggressive subtype of breast cancer. In this case report of metastatic metaplastic breast carcinoma with osteosarcomatous differentiation in a female patient previously treated for invasive ductal carcinoma, we describe the new presentation of a palpable mass with associated calcifications on imaging near the site of prior partial mastectomy. This article will detail the clinical presentation, imaging findings, histopathology, and clinical course following treatment of our case. Knowledge of the clinical and imaging presentation of this rare subtype, which can present with benign features on mammography and ultrasound, can facilitate timely diagnosis as treatment paradigms evolve.http://www.sciencedirect.com/science/article/pii/S1930043323006209Metaplastic breast carcinomaOsteosarcomatousInvasive ductal carcinomaTriple negativeAggressive breast cancerBreast cancer recurrence
spellingShingle Belinda Asare, MD
Marissa Janine White, MD
Joanna Rossi, MD, MPH
Metaplastic carcinoma with osteosarcomatous differentiation in the breast: Case report
Radiology Case Reports
Metaplastic breast carcinoma
Osteosarcomatous
Invasive ductal carcinoma
Triple negative
Aggressive breast cancer
Breast cancer recurrence
title Metaplastic carcinoma with osteosarcomatous differentiation in the breast: Case report
title_full Metaplastic carcinoma with osteosarcomatous differentiation in the breast: Case report
title_fullStr Metaplastic carcinoma with osteosarcomatous differentiation in the breast: Case report
title_full_unstemmed Metaplastic carcinoma with osteosarcomatous differentiation in the breast: Case report
title_short Metaplastic carcinoma with osteosarcomatous differentiation in the breast: Case report
title_sort metaplastic carcinoma with osteosarcomatous differentiation in the breast case report
topic Metaplastic breast carcinoma
Osteosarcomatous
Invasive ductal carcinoma
Triple negative
Aggressive breast cancer
Breast cancer recurrence
url http://www.sciencedirect.com/science/article/pii/S1930043323006209
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