Predictors of mortality for patients with ST-elevation myocardial infraction after 2-year follow-up: A ST-elevation myocardial infarction cohort in Isfahan study
Background: Mortality of ST-elevation myocardial infarction (STEMI) patients is increasing in world. This study defines predictors of mortality in patients who have STEMI. Materials and Methods: This study was a part of the ST-elevated myocardial infarction cohort study in Isfahan conducted on 876 a...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Advanced Biomedical Research |
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| Online Access: | http://www.advbiores.net/article.asp?issn=2277-9175;year=2022;volume=11;issue=1;spage=116;epage=116;aulast=Jamalian |
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| author | Marjan Jamalian Hamidreza Roohafza Azam Soleimani Gholamreza Massoumi Amirhossein Mirmohammadsadeghi Neda Dorostkar Safoura Yazdekhasti Maedeh Azarm Masoumeh Sadeghi |
| author_facet | Marjan Jamalian Hamidreza Roohafza Azam Soleimani Gholamreza Massoumi Amirhossein Mirmohammadsadeghi Neda Dorostkar Safoura Yazdekhasti Maedeh Azarm Masoumeh Sadeghi |
| author_sort | Marjan Jamalian |
| collection | DOAJ |
| description | Background: Mortality of ST-elevation myocardial infarction (STEMI) patients is increasing in world. This study defines predictors of mortality in patients who have STEMI.
Materials and Methods: This study was a part of the ST-elevated myocardial infarction cohort study in Isfahan conducted on 876 acute myocardial infarction (MI) followed for 2 years that 781 patient entered. The effect of predictors of mortality includes demographic, physiological, and clinical characterizes compared in two groups alive and died patients. MACE was defined as nonfatal MI, nonfatal stroke, and atherosclerosis cardiovascular disease-related death was recorded. Univariate and multiple logistic regression analyses were performed. All analyses performed using SPSS 20.0. P < 0.05 considered statistically significant.
Results: A total 781 patients, 117 (13%) that 72 (8.5%) was in-hospital died. The mean (standard deviation) age of the patients was 60.92 (12.77) years and 705 (81.3%) patients were males. Significant factors that affected mortality on analysis of demographic and physiological parameters were age (P < 0.001), sex (P = 0.004), transfusion (P = 0.010), STEMI type (P < 0.001), number epicardial territories >50% (P = 0.001), ventilation options (P < 0.001), smoker (P = 0.003), and diabetes (P = 0.026). Significant clinical factors affected mortality were ejection fraction (EF) (P < 0.001), creatinine (P < 0.001), hemoglobin (P < 0.001), low-density lipoprotein-cholesterol (LDL-C) (P = 0.019), and systolic blood pressure (P < 0.001). Multiple logistics regression model definition significant predictors for mortality were age (P < 0.001), heart rate (HR) (P = 0.007), EF (0.039), LDL-C (P = 0.002), and preangia (P = 0.022).
Conclusion: The set of factors can increase or decrease mortality in these patients. Significant predictors of mortality STEMI patients by 2-year follow up were age, HR, EF, LDL-C, and preangia. It seems that more articles need to be done in different parts of Iran to confirm the results. |
| first_indexed | 2024-04-10T23:28:30Z |
| format | Article |
| id | doaj.art-660624a0787b4087a72052690f975cae |
| institution | Directory Open Access Journal |
| issn | 2277-9175 |
| language | English |
| last_indexed | 2024-04-10T23:28:30Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Advanced Biomedical Research |
| spelling | doaj.art-660624a0787b4087a72052690f975cae2023-01-12T11:04:52ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752022-01-0111111611610.4103/abr.abr_242_21Predictors of mortality for patients with ST-elevation myocardial infraction after 2-year follow-up: A ST-elevation myocardial infarction cohort in Isfahan studyMarjan JamalianHamidreza RoohafzaAzam SoleimaniGholamreza MassoumiAmirhossein MirmohammadsadeghiNeda DorostkarSafoura YazdekhastiMaedeh AzarmMasoumeh SadeghiBackground: Mortality of ST-elevation myocardial infarction (STEMI) patients is increasing in world. This study defines predictors of mortality in patients who have STEMI. Materials and Methods: This study was a part of the ST-elevated myocardial infarction cohort study in Isfahan conducted on 876 acute myocardial infarction (MI) followed for 2 years that 781 patient entered. The effect of predictors of mortality includes demographic, physiological, and clinical characterizes compared in two groups alive and died patients. MACE was defined as nonfatal MI, nonfatal stroke, and atherosclerosis cardiovascular disease-related death was recorded. Univariate and multiple logistic regression analyses were performed. All analyses performed using SPSS 20.0. P < 0.05 considered statistically significant. Results: A total 781 patients, 117 (13%) that 72 (8.5%) was in-hospital died. The mean (standard deviation) age of the patients was 60.92 (12.77) years and 705 (81.3%) patients were males. Significant factors that affected mortality on analysis of demographic and physiological parameters were age (P < 0.001), sex (P = 0.004), transfusion (P = 0.010), STEMI type (P < 0.001), number epicardial territories >50% (P = 0.001), ventilation options (P < 0.001), smoker (P = 0.003), and diabetes (P = 0.026). Significant clinical factors affected mortality were ejection fraction (EF) (P < 0.001), creatinine (P < 0.001), hemoglobin (P < 0.001), low-density lipoprotein-cholesterol (LDL-C) (P = 0.019), and systolic blood pressure (P < 0.001). Multiple logistics regression model definition significant predictors for mortality were age (P < 0.001), heart rate (HR) (P = 0.007), EF (0.039), LDL-C (P = 0.002), and preangia (P = 0.022). Conclusion: The set of factors can increase or decrease mortality in these patients. Significant predictors of mortality STEMI patients by 2-year follow up were age, HR, EF, LDL-C, and preangia. It seems that more articles need to be done in different parts of Iran to confirm the results.http://www.advbiores.net/article.asp?issn=2277-9175;year=2022;volume=11;issue=1;spage=116;epage=116;aulast=Jamalianlogistic regressionmortalitypredictorsst-elevation myocardial infraction |
| spellingShingle | Marjan Jamalian Hamidreza Roohafza Azam Soleimani Gholamreza Massoumi Amirhossein Mirmohammadsadeghi Neda Dorostkar Safoura Yazdekhasti Maedeh Azarm Masoumeh Sadeghi Predictors of mortality for patients with ST-elevation myocardial infraction after 2-year follow-up: A ST-elevation myocardial infarction cohort in Isfahan study Advanced Biomedical Research logistic regression mortality predictors st-elevation myocardial infraction |
| title | Predictors of mortality for patients with ST-elevation myocardial infraction after 2-year follow-up: A ST-elevation myocardial infarction cohort in Isfahan study |
| title_full | Predictors of mortality for patients with ST-elevation myocardial infraction after 2-year follow-up: A ST-elevation myocardial infarction cohort in Isfahan study |
| title_fullStr | Predictors of mortality for patients with ST-elevation myocardial infraction after 2-year follow-up: A ST-elevation myocardial infarction cohort in Isfahan study |
| title_full_unstemmed | Predictors of mortality for patients with ST-elevation myocardial infraction after 2-year follow-up: A ST-elevation myocardial infarction cohort in Isfahan study |
| title_short | Predictors of mortality for patients with ST-elevation myocardial infraction after 2-year follow-up: A ST-elevation myocardial infarction cohort in Isfahan study |
| title_sort | predictors of mortality for patients with st elevation myocardial infraction after 2 year follow up a st elevation myocardial infarction cohort in isfahan study |
| topic | logistic regression mortality predictors st-elevation myocardial infraction |
| url | http://www.advbiores.net/article.asp?issn=2277-9175;year=2022;volume=11;issue=1;spage=116;epage=116;aulast=Jamalian |
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