Evans’ syndrome in an old patient: case presentation

Introduction. Evans’ syndrome (autoimmune hemolytic anemia combined with thrombocytopenia) is a rare hematological syndrome in the elderly. Case report. A 94-year-old patient was diagnosed with Evans’ syndrome with the secretion of monoclonal protein. The disease manifested initially by a periodi...

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Main Authors: Leonid I. DVORETSKY, Mariya A. KARNAUSHKINA, Roza M. VAKOLYUK, Nelly V. DUBROVSKAYA
Format: Article
Language:English
Published: Balkan Medical Union 2019-12-01
Series:Archives of the Balkan Medical Union
Subjects:
Online Access:https://umbalk.org/wp-content/uploads/2019/11/27.EVANS-SYNDROME-IN-AN-OLD-PATIENT.pdf
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author Leonid I. DVORETSKY
Mariya A. KARNAUSHKINA
Roza M. VAKOLYUK
Nelly V. DUBROVSKAYA
author_facet Leonid I. DVORETSKY
Mariya A. KARNAUSHKINA
Roza M. VAKOLYUK
Nelly V. DUBROVSKAYA
author_sort Leonid I. DVORETSKY
collection DOAJ
description Introduction. Evans’ syndrome (autoimmune hemolytic anemia combined with thrombocytopenia) is a rare hematological syndrome in the elderly. Case report. A 94-year-old patient was diagnosed with Evans’ syndrome with the secretion of monoclonal protein. The disease manifested initially by a periodic decrease in hemoglobin and platelet counts, accompanied by a deterioration of the clinical condition, and the development of a hemorrhagic syndrome. Long-term glucocorticoid therapy led to the development of osteoporosis, complicated by compression fracture of the lumbar vertebra. The main clinical manifestations of the disease (pain, limited mobility) were associated with the development of this complication. Conclusions. Diagnosis of Evans’ syndrome in elderly patients requires the exclusion of other similar diseases. Long-term glucocorticoid treatment can cause complications, such as osteoporosis with a risk of vertebral fracture. The resulting complications can disrupt the quality of life to a much greater extent than the underlying disease. When choosing a treatment for elderly patients with Evans’ syndrome, it is necessary to consider the possible benefits and the risk of complications.
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spelling doaj.art-6607c743c1824fa4a9b3c931880dfcb32022-12-21T18:58:58ZengBalkan Medical UnionArchives of the Balkan Medical Union1584-92442558-815X2019-12-0154478178610.31688/ABMU.2019.54.4.27Evans’ syndrome in an old patient: case presentationLeonid I. DVORETSKYMariya A. KARNAUSHKINARoza M. VAKOLYUKNelly V. DUBROVSKAYAIntroduction. Evans’ syndrome (autoimmune hemolytic anemia combined with thrombocytopenia) is a rare hematological syndrome in the elderly. Case report. A 94-year-old patient was diagnosed with Evans’ syndrome with the secretion of monoclonal protein. The disease manifested initially by a periodic decrease in hemoglobin and platelet counts, accompanied by a deterioration of the clinical condition, and the development of a hemorrhagic syndrome. Long-term glucocorticoid therapy led to the development of osteoporosis, complicated by compression fracture of the lumbar vertebra. The main clinical manifestations of the disease (pain, limited mobility) were associated with the development of this complication. Conclusions. Diagnosis of Evans’ syndrome in elderly patients requires the exclusion of other similar diseases. Long-term glucocorticoid treatment can cause complications, such as osteoporosis with a risk of vertebral fracture. The resulting complications can disrupt the quality of life to a much greater extent than the underlying disease. When choosing a treatment for elderly patients with Evans’ syndrome, it is necessary to consider the possible benefits and the risk of complications.https://umbalk.org/wp-content/uploads/2019/11/27.EVANS-SYNDROME-IN-AN-OLD-PATIENT.pdfevans’ syndromeautoimmune hemolytic anemiaimmune thrombocytopeniaelderly
spellingShingle Leonid I. DVORETSKY
Mariya A. KARNAUSHKINA
Roza M. VAKOLYUK
Nelly V. DUBROVSKAYA
Evans’ syndrome in an old patient: case presentation
Archives of the Balkan Medical Union
evans’ syndrome
autoimmune hemolytic anemia
immune thrombocytopenia
elderly
title Evans’ syndrome in an old patient: case presentation
title_full Evans’ syndrome in an old patient: case presentation
title_fullStr Evans’ syndrome in an old patient: case presentation
title_full_unstemmed Evans’ syndrome in an old patient: case presentation
title_short Evans’ syndrome in an old patient: case presentation
title_sort evans syndrome in an old patient case presentation
topic evans’ syndrome
autoimmune hemolytic anemia
immune thrombocytopenia
elderly
url https://umbalk.org/wp-content/uploads/2019/11/27.EVANS-SYNDROME-IN-AN-OLD-PATIENT.pdf
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AT nellyvdubrovskaya evanssyndromeinanoldpatientcasepresentation