NS1-based ELISA test efficiently detects dengue infections without cross-reactivity with Zika virus

NS1-based ELISA test efficiently detects dengue infections without cross-reactivity with Zika virus

Objectives: The aim of this study was to achieve greater specificity of dengue virus (DENV) serological tests based on a recombinant antigen derived from non-structural protein 1 (ΔNS1) with regard to cross-reactive Zika virus (ZIKV) anti-NS1 antibody responses. This is of relevance in endemic regio...

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Bibliographic Details
Main Authors: Samuel Santos Pereira, Robert Andreata-Santos, Lennon Ramos Pereira, Camila Pereira Soares, Alvina Clara Félix, Patrícia de Mello Jungmann Cardoso de Andrade, Edison Luís Durigon, Camila Malta Romano, Luís Carlos de Souza Ferreira
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:International Journal of Infectious Diseases
Subjects:
Dengue virus
Serological diagnosis
NS1
ELISA
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971221007190

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