Assessing the safety of physician-directed nurse-administered propofol sedation in low-risk patients undergoing endoscopy and colonoscopy

Background and study aims Physician-directed nurse-administered balanced propofol sedation (PhD NAPS) in patients undergoing endoscopy and/or colonoscopy is being increasingly utilized worldwide. However, this method of sedation is not universally employed in Australian hospitals due to concerns sur...

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Main Authors: Dharshan Sathananthan, Edward Young, Garry Nind, Biju George, Angelie Ashby, Sharon Drummond, Kasia Redel, Neville Green, Rajvinder Singh
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2017-02-01
Series:Endoscopy International Open
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-121667
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author Dharshan Sathananthan
Edward Young
Garry Nind
Biju George
Angelie Ashby
Sharon Drummond
Kasia Redel
Neville Green
Rajvinder Singh
author_facet Dharshan Sathananthan
Edward Young
Garry Nind
Biju George
Angelie Ashby
Sharon Drummond
Kasia Redel
Neville Green
Rajvinder Singh
author_sort Dharshan Sathananthan
collection DOAJ
description Background and study aims Physician-directed nurse-administered balanced propofol sedation (PhD NAPS) in patients undergoing endoscopy and/or colonoscopy is being increasingly utilized worldwide. However, this method of sedation is not universally employed in Australian hospitals due to concerns surrounding its safety. The aim of this study was to assess the safety of PhD NAPS in low-risk patients undergoing endoscopy and/or colonoscopy. Patients and methods This study was conducted at a single tertiary teaching hospital in Adelaide, Australia. It was a prospective study involving 1000 patients with an ASA score of 1 – 3 presenting with any indication for endoscopy, colonoscopy or both. A total of 981 patients (451 male) with a mean age of 53 years (range: 16 – 87) were recruited from January 2010 to October 2012. 440 endoscopies, 420 colonoscopies, and 121 combined procedures were performed. The intra-procedural adverse events (AEs) were recorded. Results There were no major intra-procedural adverse events. Minor AEs occurred in 6.42 % of patients, and resolved spontaneously or with intravenous fluid boluses in all cases. Conclusion PhD NAPS is safe when the proceduralist and nursing staff are adequately trained and strict patient selection criteria are used.
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spelling doaj.art-660f5ab17bcf49ffa6f5c7665876b6fd2022-12-21T19:56:05ZengGeorg Thieme Verlag KGEndoscopy International Open2364-37222196-97362017-02-010502E110E11510.1055/s-0042-121667Assessing the safety of physician-directed nurse-administered propofol sedation in low-risk patients undergoing endoscopy and colonoscopyDharshan Sathananthan0Edward Young1Garry Nind2Biju George3Angelie Ashby4Sharon Drummond5Kasia Redel6Neville Green7Rajvinder Singh8Royal Adelaide Hospital – Gastroenerology, Adelaide, South AustraliaUniversity of Adelaide Medical School, Adelaide, South AustraliaLyell McEwin Hospital – Gastroenterology, Adelaide, South AustraliaLyell McEwin Hospital – Gastroenterology, Adelaide, South AustraliaUniversity of Adelaide/Lyell McEwin Hospital, Endoscopy Unit, Elizabeth Vale, South AustraliaUniversity of Adelaide/Lyell McEwin Hospital, Endoscopy Unit, Elizabeth Vale, South AustraliaUniversity of Adelaide/Lyell McEwin Hospital, Endoscopy Unit, Elizabeth Vale, South AustraliaLyell McEwin Hospital – Anaesthetics, Elizabeth Vale, South AustraliaLyell McEwin Hospital – Gastroenterology, Adelaide, South AustraliaBackground and study aims Physician-directed nurse-administered balanced propofol sedation (PhD NAPS) in patients undergoing endoscopy and/or colonoscopy is being increasingly utilized worldwide. However, this method of sedation is not universally employed in Australian hospitals due to concerns surrounding its safety. The aim of this study was to assess the safety of PhD NAPS in low-risk patients undergoing endoscopy and/or colonoscopy. Patients and methods This study was conducted at a single tertiary teaching hospital in Adelaide, Australia. It was a prospective study involving 1000 patients with an ASA score of 1 – 3 presenting with any indication for endoscopy, colonoscopy or both. A total of 981 patients (451 male) with a mean age of 53 years (range: 16 – 87) were recruited from January 2010 to October 2012. 440 endoscopies, 420 colonoscopies, and 121 combined procedures were performed. The intra-procedural adverse events (AEs) were recorded. Results There were no major intra-procedural adverse events. Minor AEs occurred in 6.42 % of patients, and resolved spontaneously or with intravenous fluid boluses in all cases. Conclusion PhD NAPS is safe when the proceduralist and nursing staff are adequately trained and strict patient selection criteria are used.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-121667
spellingShingle Dharshan Sathananthan
Edward Young
Garry Nind
Biju George
Angelie Ashby
Sharon Drummond
Kasia Redel
Neville Green
Rajvinder Singh
Assessing the safety of physician-directed nurse-administered propofol sedation in low-risk patients undergoing endoscopy and colonoscopy
Endoscopy International Open
title Assessing the safety of physician-directed nurse-administered propofol sedation in low-risk patients undergoing endoscopy and colonoscopy
title_full Assessing the safety of physician-directed nurse-administered propofol sedation in low-risk patients undergoing endoscopy and colonoscopy
title_fullStr Assessing the safety of physician-directed nurse-administered propofol sedation in low-risk patients undergoing endoscopy and colonoscopy
title_full_unstemmed Assessing the safety of physician-directed nurse-administered propofol sedation in low-risk patients undergoing endoscopy and colonoscopy
title_short Assessing the safety of physician-directed nurse-administered propofol sedation in low-risk patients undergoing endoscopy and colonoscopy
title_sort assessing the safety of physician directed nurse administered propofol sedation in low risk patients undergoing endoscopy and colonoscopy
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-121667
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