A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis
Alpha 1-antitrypsin (AAT) belongs to the family of serpins (serine protease inhibitors). Loop sheet polymerization is the pathology behind serpinopathies which encompasses AAT, anti-thrombin III and neuroserpin deficiency. To the best of our knowledge, we report the first case of alpha 1-antitrypsin...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Annals of Thoracic Medicine |
| Subjects: | |
| Online Access: | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2014;volume=9;issue=1;spage=39;epage=41;aulast=Gupta |
| _version_ | 1818339218954387456 |
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| author | Raghav Gupta Srilekha Sridhara John A Wood |
| author_facet | Raghav Gupta Srilekha Sridhara John A Wood |
| author_sort | Raghav Gupta |
| collection | DOAJ |
| description | Alpha 1-antitrypsin (AAT) belongs to the family of serpins (serine protease inhibitors). Loop sheet polymerization is the pathology behind serpinopathies which encompasses AAT, anti-thrombin III and neuroserpin deficiency. To the best of our knowledge, we report the first case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis without any concomitant use of drugs. |
| first_indexed | 2024-12-13T15:23:31Z |
| format | Article |
| id | doaj.art-66102e80949f43848b71d9260fd6ab37 |
| institution | Directory Open Access Journal |
| issn | 1817-1737 1998-3557 |
| language | English |
| last_indexed | 2024-12-13T15:23:31Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Thoracic Medicine |
| spelling | doaj.art-66102e80949f43848b71d9260fd6ab372022-12-21T23:40:28ZengWolters Kluwer Medknow PublicationsAnnals of Thoracic Medicine1817-17371998-35572014-01-0191394110.4103/1817-1737.124442A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosisRaghav GuptaSrilekha SridharaJohn A WoodAlpha 1-antitrypsin (AAT) belongs to the family of serpins (serine protease inhibitors). Loop sheet polymerization is the pathology behind serpinopathies which encompasses AAT, anti-thrombin III and neuroserpin deficiency. To the best of our knowledge, we report the first case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis without any concomitant use of drugs.http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2014;volume=9;issue=1;spage=39;epage=41;aulast=GuptaAlpha 1-antitrypsin deficiencyhypogammaglobulinemiarecurrent pulmonary thrombosisserpinopathies |
| spellingShingle | Raghav Gupta Srilekha Sridhara John A Wood A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis Annals of Thoracic Medicine Alpha 1-antitrypsin deficiency hypogammaglobulinemia recurrent pulmonary thrombosis serpinopathies |
| title | A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis |
| title_full | A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis |
| title_fullStr | A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis |
| title_full_unstemmed | A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis |
| title_short | A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis |
| title_sort | rare case of alpha 1 antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis |
| topic | Alpha 1-antitrypsin deficiency hypogammaglobulinemia recurrent pulmonary thrombosis serpinopathies |
| url | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2014;volume=9;issue=1;spage=39;epage=41;aulast=Gupta |
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