Synovium is a sensitive tissue for mapping the negative effects of systemic iron overload in osteoarthritis: identification and validation of two potential targets

Synovium is a sensitive tissue for mapping the negative effects of systemic iron overload in osteoarthritis: identification and validation of two potential targets

Abstract Background The prevention and treatment of osteoarthritis (OA) pose a major challenge in its research. The synovium is a critical tissue in the systematic treatment of OA. The present study aimed to investigate potential target genes and their correlation with iron overload in OA patients....

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Bibliographic Details
Main Authors: Zhuangzhuang Jin, He Zhang, Lunhao Bai, Lingyu Yue, Weiming Zhang, Jiajian Liang, Bohan Chang, Yue Yang, Zhehan Hu, Liang Chen, Chuanji Guo
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Translational Medicine
Subjects:
Bioinformatics analysis
Iron overload
Osteoarthritis
Single-cell RNA-seq analysis
Synovium
Validation experiments
Online Access:https://doi.org/10.1186/s12967-023-04541-5

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