Behavioral experience induces zif268 expression in mature granule cells but suppresses its expression in immature granule cells

Behavioral experience induces zif268 expression in mature granule cells but suppresses its expression in immature granule cells

Thousands of neurons are born each day in the dentate gyrus (DG), but many of these cells die before reaching maturity. Both death and survival of adult-born neurons are regulated by neuronal activity in DG. The immediate-early gene (IEG) zif268 is an important mediator of these effects, as its expr...

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Bibliographic Details
Main Authors: Kylie A. Huckleberry, Gary A. Kane, Rita eMathis, Sarah eCook, Jon E. Clutton, Michael R. Drew
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Systems Neuroscience
Subjects:
Behavior
Dentate Gyrus
Hippocampus
Memory
adult neurogenesis
Zif268
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2015.00118/full

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