Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic Reviews
This overview aimed to evaluate the methods, quality, and outcomes of systematic reviews (SRs) conducted to investigate the effects of platelet-rich fibrin (PRF) in dental sockets on promoting bone regeneration and soft tissue healing and diminishing the incidence of pain, swelling, trismus, and alv...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/10/17/5750 |
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| author | Vittorio Moraschini Carlos Fernando de Almeida Barros Mourão Rafael Coutinho de Mello Machado Jhonathan Raphaell Barros Nascimento Kayvon Javid Monica Diuana Calasans-Maia Angelo Cardarelli Pietro Montemezzi Jose de Albuquerque Calasans-Maia |
| author_facet | Vittorio Moraschini Carlos Fernando de Almeida Barros Mourão Rafael Coutinho de Mello Machado Jhonathan Raphaell Barros Nascimento Kayvon Javid Monica Diuana Calasans-Maia Angelo Cardarelli Pietro Montemezzi Jose de Albuquerque Calasans-Maia |
| author_sort | Vittorio Moraschini |
| collection | DOAJ |
| description | This overview aimed to evaluate the methods, quality, and outcomes of systematic reviews (SRs) conducted to investigate the effects of platelet-rich fibrin (PRF) in dental sockets on promoting bone regeneration and soft tissue healing and diminishing the incidence of pain, swelling, trismus, and alveolar osteitis after tooth extraction. An electronic search without date or language restriction was done in PubMed/MEDLINE, Cochrane, and Web of Science until March 2020. Eligibility criteria included SRs that assessed the effect of PRF for human alveolar socket preservation. The quality assessment of the included studies was performed using AMSTAR 2 guidelines. The protocol of this overview was recorded in PROSPERO under the number CRD42018089617. The search and selection process yielded 13 studies published between 2011 and 2018. The analysis of the studies showed inconclusive data for the effect of the PRF and the dimensional changes. There is no definitive evidence for the impact of using PRF alone on bone regeneration in post-extraction sockets. The use of PRF improves soft tissue healing and reduces pain, bleeding, and osteitis in post-extraction sockets. |
| first_indexed | 2024-03-10T17:08:46Z |
| format | Article |
| id | doaj.art-661948e139274493b4e6ee36d4c477d4 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T17:08:46Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-661948e139274493b4e6ee36d4c477d42023-11-20T10:42:46ZengMDPI AGApplied Sciences2076-34172020-08-011017575010.3390/app10175750Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic ReviewsVittorio Moraschini0Carlos Fernando de Almeida Barros Mourão1Rafael Coutinho de Mello Machado2Jhonathan Raphaell Barros Nascimento3Kayvon Javid4Monica Diuana Calasans-Maia5Angelo Cardarelli6Pietro Montemezzi7Jose de Albuquerque Calasans-Maia8Department of Research in Periodontics, School of Dentistry, Universidade Veiga de Almeida, Rio de Janeiro 20271-020, BrazilPostgraduate Program in Dentistry School, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24020-140, BrazilPostgraduate Program in Dentistry School, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24020-140, BrazilPostgraduate Program in Dentistry School, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24020-140, BrazilPostgraduate Program in Dentistry School, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24020-140, BrazilDepartment of Oral Surgery, School of Dentistry, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24220-900, BrazilPrivate Practice, 86170 Isernia, ItalyPrivate Practice, 24121 Bergamo, ItalyDepartment of Orthodontics, School of Dentistry, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24020-140, BrazilThis overview aimed to evaluate the methods, quality, and outcomes of systematic reviews (SRs) conducted to investigate the effects of platelet-rich fibrin (PRF) in dental sockets on promoting bone regeneration and soft tissue healing and diminishing the incidence of pain, swelling, trismus, and alveolar osteitis after tooth extraction. An electronic search without date or language restriction was done in PubMed/MEDLINE, Cochrane, and Web of Science until March 2020. Eligibility criteria included SRs that assessed the effect of PRF for human alveolar socket preservation. The quality assessment of the included studies was performed using AMSTAR 2 guidelines. The protocol of this overview was recorded in PROSPERO under the number CRD42018089617. The search and selection process yielded 13 studies published between 2011 and 2018. The analysis of the studies showed inconclusive data for the effect of the PRF and the dimensional changes. There is no definitive evidence for the impact of using PRF alone on bone regeneration in post-extraction sockets. The use of PRF improves soft tissue healing and reduces pain, bleeding, and osteitis in post-extraction sockets.https://www.mdpi.com/2076-3417/10/17/5750alveolar socket preservationplatelet-rich fibrinPRFgrowth factorstooth extraction |
| spellingShingle | Vittorio Moraschini Carlos Fernando de Almeida Barros Mourão Rafael Coutinho de Mello Machado Jhonathan Raphaell Barros Nascimento Kayvon Javid Monica Diuana Calasans-Maia Angelo Cardarelli Pietro Montemezzi Jose de Albuquerque Calasans-Maia Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic Reviews Applied Sciences alveolar socket preservation platelet-rich fibrin PRF growth factors tooth extraction |
| title | Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic Reviews |
| title_full | Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic Reviews |
| title_fullStr | Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic Reviews |
| title_full_unstemmed | Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic Reviews |
| title_short | Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic Reviews |
| title_sort | does platelet rich fibrin decrease dimensional changes and improve postoperative comfort in post extraction sockets an overview of systematic reviews |
| topic | alveolar socket preservation platelet-rich fibrin PRF growth factors tooth extraction |
| url | https://www.mdpi.com/2076-3417/10/17/5750 |
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