Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell Carcinoma
(1) Background: Many transporters of the SLC22 family (e.g., OAT1, OAT3, OCT2, URAT1, and OCTN2) are highly expressed in the kidney. They transport drugs, metabolites, signaling molecules, antioxidants, nutrients, and gut microbiome products. According to the Remote Sensing and Signaling Theory, SLC...
Main Authors: | Thomas C. Whisenant, Sanjay K. Nigam |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-09-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/14/19/4772 |
Similar Items
-
Downregulation of organic cation transporters OCT1 (<it>SLC22A1</it>) and OCT3 (<it>SLC22A3</it>) in human hepatocellular carcinoma and their prognostic significance
by: Heise Michael, et al.
Published: (2012-03-01) -
Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine
by: Seung Hoon Lee, et al.
Published: (2019-03-01) -
The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans
by: Anne T. Nies, et al.
Published: (2020-08-01) -
Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter
by: Darren eMoss, et al.
Published: (2015-04-01) -
Expression and Its Clinical Significance of SLC22A18 in Non-small Cell Lung Cancer
by: Ming LEI, et al.
Published: (2012-01-01)