Joint hemorrhage accelerates cartilage degeneration in a rat immobilized knee model

Joint hemorrhage accelerates cartilage degeneration in a rat immobilized knee model

Abstract Background Joint hemorrhage is caused by trauma, ligament reconstruction surgery, and bleeding disorders such as hemophilia. Recurrence of hemorrhage in the joint space induces hemosiderotic synovitis and oxidative stress, resulting in both articular cartilage degeneration and arthropathy....

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Main Authors: Yasuhito Sogi, Yutaka Yabe, Yoshihiro Hagiwara, Masahiro Tsuchiya, Yoshito Onoda, Takuya Sekiguchi, Nobuyuki Itaya, Shinichiro Yoshida, Toshihisa Yano, Kazuaki Suzuki, Takahiro Onoki, Eiji Itoi
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Cartilage degeneration
Joint hemorrhage
Joint immobilization
Mechanical stress
Online Access:http://link.springer.com/article/10.1186/s12891-020-03795-0

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