The role of antihypertensive drugs in patients with preeclampsia and how to prevent it
HIGHLIGHTS 1. Preeclampsia, or hypertension in pregnancy, remains a serious problem that has negative short and long-term consequences for the mother and the baby. 2. The use of antihypertensive medications has its own precautions as it they may harm the fetus. 3. Prophylactic measures with minima...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2022-12-01
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| Series: | Majalah Obstetri dan Ginekologi |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/MOG/article/view/30879 |
| _version_ | 1798003887965208576 |
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| author | I Gde Sastra Winata I Wayan Agus Surya Pradnyana Maria Septiana Parmonang Aroean |
| author_facet | I Gde Sastra Winata I Wayan Agus Surya Pradnyana Maria Septiana Parmonang Aroean |
| author_sort | I Gde Sastra Winata |
| collection | DOAJ |
| description | HIGHLIGHTS
1. Preeclampsia, or hypertension in pregnancy, remains a serious problem that has negative short and long-term consequences for the mother and the baby.
2. The use of antihypertensive medications has its own precautions as it they may harm the fetus.
3. Prophylactic measures with minimal or moderate impact may be beneficial for mothers with hypertension in pregnancy.
ABSTRACT
Treatment of hypertension in pregnancy, such as preeclampsia (PE), is still a difficult issue with negative short and long-term consequences for both the mother and the baby. Screening for preeclampsia at 11-13 weeks' gestation using a combination of maternal demographic characteristics and medical history with biomarker measurements can identify approximately 75% of women who develop premature preeclampsia with delivery at 37 weeks gestation and 90% of those with early preeclampsia. Preeclampsia has a 10% positive screen rate at 32 weeks. Another important worry on the use of antihypertensive medications during pregnancy is the potential harm to the fetus. Methyldopa, hydralazine, labetalol, and nifedipine are some common antihypertensive medications. Aspirin use is frequently related to a decrease in the prevention of early preeclampsia, but it must be accompanied by medication adherence. Aspirin can be coupled with heparin. Recent investigations on the use of furosemide and nifedipine in preeclampsia have also revealed a new combination. |
| first_indexed | 2024-04-11T12:14:56Z |
| format | Article |
| id | doaj.art-661c8dfdc75545a8976ed4d39cd31e30 |
| institution | Directory Open Access Journal |
| issn | 0854-0381 2598-1013 |
| language | English |
| last_indexed | 2024-04-11T12:14:56Z |
| publishDate | 2022-12-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Majalah Obstetri dan Ginekologi |
| spelling | doaj.art-661c8dfdc75545a8976ed4d39cd31e302022-12-22T04:24:20ZengUniversitas AirlanggaMajalah Obstetri dan Ginekologi0854-03812598-10132022-12-0130314615310.20473/mog.V30I32022.146-15325268The role of antihypertensive drugs in patients with preeclampsia and how to prevent itI Gde Sastra Winata0https://orcid.org/0000-0001-5975-0437I Wayan Agus Surya Pradnyana1https://orcid.org/0000-0002-7095-4956Maria Septiana Parmonang Aroean2Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Udayana, Sanglah General Hospital, Denpasar, BaliFaculty of Medicine, Universitas Udayana, Denpasar, BaliFaculty of Medicine, Universitas Udayana, Denpasar, BaliHIGHLIGHTS 1. Preeclampsia, or hypertension in pregnancy, remains a serious problem that has negative short and long-term consequences for the mother and the baby. 2. The use of antihypertensive medications has its own precautions as it they may harm the fetus. 3. Prophylactic measures with minimal or moderate impact may be beneficial for mothers with hypertension in pregnancy. ABSTRACT Treatment of hypertension in pregnancy, such as preeclampsia (PE), is still a difficult issue with negative short and long-term consequences for both the mother and the baby. Screening for preeclampsia at 11-13 weeks' gestation using a combination of maternal demographic characteristics and medical history with biomarker measurements can identify approximately 75% of women who develop premature preeclampsia with delivery at 37 weeks gestation and 90% of those with early preeclampsia. Preeclampsia has a 10% positive screen rate at 32 weeks. Another important worry on the use of antihypertensive medications during pregnancy is the potential harm to the fetus. Methyldopa, hydralazine, labetalol, and nifedipine are some common antihypertensive medications. Aspirin use is frequently related to a decrease in the prevention of early preeclampsia, but it must be accompanied by medication adherence. Aspirin can be coupled with heparin. Recent investigations on the use of furosemide and nifedipine in preeclampsia have also revealed a new combination.https://e-journal.unair.ac.id/MOG/article/view/30879preeclampsiaantihypertensive methyldopanifedipinematernal health |
| spellingShingle | I Gde Sastra Winata I Wayan Agus Surya Pradnyana Maria Septiana Parmonang Aroean The role of antihypertensive drugs in patients with preeclampsia and how to prevent it Majalah Obstetri dan Ginekologi preeclampsia antihypertensive methyldopa nifedipine maternal health |
| title | The role of antihypertensive drugs in patients with preeclampsia and how to prevent it |
| title_full | The role of antihypertensive drugs in patients with preeclampsia and how to prevent it |
| title_fullStr | The role of antihypertensive drugs in patients with preeclampsia and how to prevent it |
| title_full_unstemmed | The role of antihypertensive drugs in patients with preeclampsia and how to prevent it |
| title_short | The role of antihypertensive drugs in patients with preeclampsia and how to prevent it |
| title_sort | role of antihypertensive drugs in patients with preeclampsia and how to prevent it |
| topic | preeclampsia antihypertensive methyldopa nifedipine maternal health |
| url | https://e-journal.unair.ac.id/MOG/article/view/30879 |
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