Significant impact of transperineal template biopsy of the prostate at a single tertiary institution
Objective: The objective was to review the impact of transperineal biopsy (TPB) at our institution by assessing rates of cancer detection/grading, treatment outcomes and complications. Patients and Methods: A retrospective review of TPBs between 2009 and 2013 was performed. Variables included reason...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015-01-01
|
| Series: | Urology Annals |
| Subjects: | |
| Online Access: | http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=4;spage=428;epage=432;aulast=Huang |
| _version_ | 1811322293287124992 |
|---|---|
| author | Sean Huang Fairleigh Reeves Jessica Preece Prassannah Satasivam Peter Royce Jeremy P Grummet |
| author_facet | Sean Huang Fairleigh Reeves Jessica Preece Prassannah Satasivam Peter Royce Jeremy P Grummet |
| author_sort | Sean Huang |
| collection | DOAJ |
| description | Objective: The objective was to review the impact of transperineal biopsy (TPB) at our institution by assessing rates of cancer detection/grading, treatment outcomes and complications.
Patients and Methods: A retrospective review of TPBs between 2009 and 2013 was performed. Variables included reason for TPB, age, prostate-specific antigen, previous histology, TPB histology, and management outcomes.
Results: In total, 110 patients underwent 111 TPBs at our institution. On average, 22 cores were taken from each procedure. Disease-upgrade occurred in 37.5% of active surveillance patients, 35% of patients with previous negative transrectal ultrasound, and 58.8% in patients undergoing TPB for other reasons. Of these patients, anterior and/or transition zones were involved in 66%, 79%, and 80%, respectively. Involvement in anterior and/or transition zones only occurred in 40%, 37%, and 10%, respectively.
About 77% of patients with disease-upgrading underwent treatment with curative intent. Complications included a 6.3% rate of acute urinary retention and 2.7% of clot retention, with no episodes of urosepsis.
Conclusions: Transperineal biopsy at our institution showed a high rate of disease-upgrading, with a large proportion involving anterior and transition zones. A significant amount of patients went on to receive curative treatment. TPB is a valuable diagnostic procedure with minimal risk of developing urosepsis. We believe TBP should be offered as an option for all repeat prostate biopsies and considered as an option for initial prostate biopsy. |
| first_indexed | 2024-04-13T13:32:35Z |
| format | Article |
| id | doaj.art-662091a3c72d47e19f00cea91502eeed |
| institution | Directory Open Access Journal |
| issn | 0974-7796 0974-7834 |
| language | English |
| last_indexed | 2024-04-13T13:32:35Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Urology Annals |
| spelling | doaj.art-662091a3c72d47e19f00cea91502eeed2022-12-22T02:44:53ZengWolters Kluwer Medknow PublicationsUrology Annals0974-77960974-78342015-01-017442843210.4103/0974-7796.152052Significant impact of transperineal template biopsy of the prostate at a single tertiary institutionSean HuangFairleigh ReevesJessica PreecePrassannah SatasivamPeter RoyceJeremy P GrummetObjective: The objective was to review the impact of transperineal biopsy (TPB) at our institution by assessing rates of cancer detection/grading, treatment outcomes and complications. Patients and Methods: A retrospective review of TPBs between 2009 and 2013 was performed. Variables included reason for TPB, age, prostate-specific antigen, previous histology, TPB histology, and management outcomes. Results: In total, 110 patients underwent 111 TPBs at our institution. On average, 22 cores were taken from each procedure. Disease-upgrade occurred in 37.5% of active surveillance patients, 35% of patients with previous negative transrectal ultrasound, and 58.8% in patients undergoing TPB for other reasons. Of these patients, anterior and/or transition zones were involved in 66%, 79%, and 80%, respectively. Involvement in anterior and/or transition zones only occurred in 40%, 37%, and 10%, respectively. About 77% of patients with disease-upgrading underwent treatment with curative intent. Complications included a 6.3% rate of acute urinary retention and 2.7% of clot retention, with no episodes of urosepsis. Conclusions: Transperineal biopsy at our institution showed a high rate of disease-upgrading, with a large proportion involving anterior and transition zones. A significant amount of patients went on to receive curative treatment. TPB is a valuable diagnostic procedure with minimal risk of developing urosepsis. We believe TBP should be offered as an option for all repeat prostate biopsies and considered as an option for initial prostate biopsy.http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=4;spage=428;epage=432;aulast=HuangBiopsycomplicationsprostateprostatic neoplasmssepsistransperineal |
| spellingShingle | Sean Huang Fairleigh Reeves Jessica Preece Prassannah Satasivam Peter Royce Jeremy P Grummet Significant impact of transperineal template biopsy of the prostate at a single tertiary institution Urology Annals Biopsy complications prostate prostatic neoplasms sepsis transperineal |
| title | Significant impact of transperineal template biopsy of the prostate at a single tertiary institution |
| title_full | Significant impact of transperineal template biopsy of the prostate at a single tertiary institution |
| title_fullStr | Significant impact of transperineal template biopsy of the prostate at a single tertiary institution |
| title_full_unstemmed | Significant impact of transperineal template biopsy of the prostate at a single tertiary institution |
| title_short | Significant impact of transperineal template biopsy of the prostate at a single tertiary institution |
| title_sort | significant impact of transperineal template biopsy of the prostate at a single tertiary institution |
| topic | Biopsy complications prostate prostatic neoplasms sepsis transperineal |
| url | http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=4;spage=428;epage=432;aulast=Huang |
| work_keys_str_mv | AT seanhuang significantimpactoftransperinealtemplatebiopsyoftheprostateatasingletertiaryinstitution AT fairleighreeves significantimpactoftransperinealtemplatebiopsyoftheprostateatasingletertiaryinstitution AT jessicapreece significantimpactoftransperinealtemplatebiopsyoftheprostateatasingletertiaryinstitution AT prassannahsatasivam significantimpactoftransperinealtemplatebiopsyoftheprostateatasingletertiaryinstitution AT peterroyce significantimpactoftransperinealtemplatebiopsyoftheprostateatasingletertiaryinstitution AT jeremypgrummet significantimpactoftransperinealtemplatebiopsyoftheprostateatasingletertiaryinstitution |