The functions of SET domain bifurcated histone lysine methyltransferase 1 (SETDB1) in biological process and disease

Abstract Histone methyltransferase SETDB1 (SET domain bifurcated histone lysine methyltransferase 1, also known as ESET or KMT1E) is known to be involved in the deposition of the di- and tri-methyl marks on H3K9 (H3K9me2 and H3K9me3), which are associated with transcription repression. SETDB1 exerts...

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Main Authors: Hanshen Luo, Xingliang Wu, Xue-Hai Zhu, Xin Yi, Dunfeng Du, Ding-Sheng Jiang
格式: 文件
语言:English
出版: BMC 2023-12-01
丛编:Epigenetics & Chromatin
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在线阅读:https://doi.org/10.1186/s13072-023-00519-1