Comparison of central corneal thickness with four noncontact devices: An agreement analysis of swept-source technology
Purpose: The purpose of this study was to compare the central corneal thickness (CCT) measurements of four noncontact devices in healthy eyes. Materials and Methods: In a sample of 45 healthy controls, CCT was measured using an optical biometer (IOLMaster 700) based on swept-source optical coherence...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=6;spage=461;epage=465;aulast=Ozyol |
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| author | Erhan Ozyol Pelin Özyol |
| author_facet | Erhan Ozyol Pelin Özyol |
| author_sort | Erhan Ozyol |
| collection | DOAJ |
| description | Purpose: The purpose of this study was to compare the central corneal thickness (CCT) measurements of four noncontact devices in healthy eyes. Materials and Methods: In a sample of 45 healthy controls, CCT was measured using an optical biometer (IOLMaster 700) based on swept-source optical coherence tomography (SS-OCT), high-resolution rotating Scheimpflug camera system (Pentacam HR), spectral-domain OCT (SD-OCT) device with an anterior segment module (Spectralis), and noncontact pachymetry (NCP) device (Topcon TRK-2P). Agreement among the devices was analyzed using mean differences (i.e., bias) and Bland–Altman analysis with 95% limits of agreement (LoA). Results: Mean CCT measurements were 537.5 ± 47.5 μm for SS-OCT optical biometer, 532.3 ± 43.8 μm for Scheimpflug system, 521.3 ± 44.7 μm for SD-OCT device, and 518.0 ± 43.1 μm for NCP (P < 0.001). The SD-OCT device and NCP showed the closest agreement, with a bias of 2.6 μm (95% LoA, −3.6–8.8 μm), whereas the SS-OCT optical biometer and NCP showed the least agreement, with a bias of 18.7 μm (95% LoA, −2.1–39.5 μm). Bias was 16.1 μm (95% LoA, −3.1–35.3 μm) for SS-OCT optical biometer and SD-OCT, 5.1 μm (95% LoA, −6.8–17.0 μm) for SS-OCT optical biometer and Scheimpflug system, 10.9 μm (95% LoA, −15.1–36.9 μm) for SD-OCT device and Scheimpflug system, and 13.6 μm (95% LoA, −5–32.2 μm) for Scheimpflug system and NCP. Conclusions: SS-OCT optical biometer overestimates CCT measurements compared to Scheimpflug system, SD-OCT device, and NCP. Given mean differences and range variations in CCT measurements between devices, SS-OCT optical biometer and Scheimpflug system are interchangeable as are SD-OCT and NCP. |
| first_indexed | 2024-04-13T13:32:35Z |
| format | Article |
| id | doaj.art-6628ec5dfe1841f9a9772bc81373124b |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-13T13:32:35Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-6628ec5dfe1841f9a9772bc81373124b2022-12-22T02:44:53ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892017-01-0165646146510.4103/ijo.IJO_618_16Comparison of central corneal thickness with four noncontact devices: An agreement analysis of swept-source technologyErhan OzyolPelin ÖzyolPurpose: The purpose of this study was to compare the central corneal thickness (CCT) measurements of four noncontact devices in healthy eyes. Materials and Methods: In a sample of 45 healthy controls, CCT was measured using an optical biometer (IOLMaster 700) based on swept-source optical coherence tomography (SS-OCT), high-resolution rotating Scheimpflug camera system (Pentacam HR), spectral-domain OCT (SD-OCT) device with an anterior segment module (Spectralis), and noncontact pachymetry (NCP) device (Topcon TRK-2P). Agreement among the devices was analyzed using mean differences (i.e., bias) and Bland–Altman analysis with 95% limits of agreement (LoA). Results: Mean CCT measurements were 537.5 ± 47.5 μm for SS-OCT optical biometer, 532.3 ± 43.8 μm for Scheimpflug system, 521.3 ± 44.7 μm for SD-OCT device, and 518.0 ± 43.1 μm for NCP (P < 0.001). The SD-OCT device and NCP showed the closest agreement, with a bias of 2.6 μm (95% LoA, −3.6–8.8 μm), whereas the SS-OCT optical biometer and NCP showed the least agreement, with a bias of 18.7 μm (95% LoA, −2.1–39.5 μm). Bias was 16.1 μm (95% LoA, −3.1–35.3 μm) for SS-OCT optical biometer and SD-OCT, 5.1 μm (95% LoA, −6.8–17.0 μm) for SS-OCT optical biometer and Scheimpflug system, 10.9 μm (95% LoA, −15.1–36.9 μm) for SD-OCT device and Scheimpflug system, and 13.6 μm (95% LoA, −5–32.2 μm) for Scheimpflug system and NCP. Conclusions: SS-OCT optical biometer overestimates CCT measurements compared to Scheimpflug system, SD-OCT device, and NCP. Given mean differences and range variations in CCT measurements between devices, SS-OCT optical biometer and Scheimpflug system are interchangeable as are SD-OCT and NCP.http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=6;spage=461;epage=465;aulast=OzyolAnterior segment optical coherence tomographycentral corneal thicknessnoncontact pachymetryScheimpflug analysis systemswept-source optical biometer |
| spellingShingle | Erhan Ozyol Pelin Özyol Comparison of central corneal thickness with four noncontact devices: An agreement analysis of swept-source technology Indian Journal of Ophthalmology Anterior segment optical coherence tomography central corneal thickness noncontact pachymetry Scheimpflug analysis system swept-source optical biometer |
| title | Comparison of central corneal thickness with four noncontact devices: An agreement analysis of swept-source technology |
| title_full | Comparison of central corneal thickness with four noncontact devices: An agreement analysis of swept-source technology |
| title_fullStr | Comparison of central corneal thickness with four noncontact devices: An agreement analysis of swept-source technology |
| title_full_unstemmed | Comparison of central corneal thickness with four noncontact devices: An agreement analysis of swept-source technology |
| title_short | Comparison of central corneal thickness with four noncontact devices: An agreement analysis of swept-source technology |
| title_sort | comparison of central corneal thickness with four noncontact devices an agreement analysis of swept source technology |
| topic | Anterior segment optical coherence tomography central corneal thickness noncontact pachymetry Scheimpflug analysis system swept-source optical biometer |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=6;spage=461;epage=465;aulast=Ozyol |
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