Cerebral tuberculoma: an entity not to ignore

Cerebral tuberculomas are a rare and serious form of tuberculosis due to the haematogenous spread of Mycobacterium Tuberculosis. Symptoms and radiologic features are nonspecific, leading sometimes to misdiagnosis. We report the case of a 60-year-old male, with a history of diffuse bilateral infiltra...

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Main Authors: Samia Frioui, Sonia Jemni
Format: Article
Language:English
Published: The Pan African Medical Journal 2016-06-01
Series:The Pan African Medical Journal
Subjects:
Online Access: https://www.panafrican-med-journal.com/content/article/24/133/pdf/133.pdf
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author Samia Frioui
Sonia Jemni
author_facet Samia Frioui
Sonia Jemni
author_sort Samia Frioui
collection DOAJ
description Cerebral tuberculomas are a rare and serious form of tuberculosis due to the haematogenous spread of Mycobacterium Tuberculosis. Symptoms and radiologic features are nonspecific, leading sometimes to misdiagnosis. We report the case of a 60-year-old male, with a history of diffuse bilateral infiltrative pulmonary disease at the stage of fibrosis, he made two generalized seizures associated with occipital headaches. CT scan showed a left frontal tumor, calcified lesion with edema around it. The patient was put under Depakine and corticosteroids. The evolution is marked by the occurrence of new seizures associated with heaviness of the right arm. Brain MRI showed a left posterior peripheral frontal meningioma with intralesional bleeding and significant edema around it with mass effect on the ipsilateral lateral ventricle. The patient was operated and the tumor was removed. In postoperative there was a Broca's aphasia with right hemiplegia. Pathological anatomical examination of the surgical specimen found a cerebromeningeal Granuloma with caseous necrosis in its pseudo tumor presentation (tuberculoma). The thoraco abdominal scan did not show any other tuberculosis lesions. The patient started antituberculosis treatment with 4 drugs (HRZE) for 2 months, followed by maintenance therapy (HR).The evolution was marked by the persistence of a right hemiplegia with Broca's aphasia. The patient was brought out in a wheelchair with functional rehabilitation sessions.
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spelling doaj.art-6628f51daed4458faf4dbf7b10b2d5f92022-12-21T19:23:27ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882016-06-012413310.11604/pamj.2016.24.133.94849484Cerebral tuberculoma: an entity not to ignoreSamia Frioui0Sonia Jemni1 Physical Medicine and Rehabilitation Department, Sahloul hospital, Sousse, Tunisia Physical Medicine and Rehabilitation Department, Sahloul hospital, Sousse, Tunisia Cerebral tuberculomas are a rare and serious form of tuberculosis due to the haematogenous spread of Mycobacterium Tuberculosis. Symptoms and radiologic features are nonspecific, leading sometimes to misdiagnosis. We report the case of a 60-year-old male, with a history of diffuse bilateral infiltrative pulmonary disease at the stage of fibrosis, he made two generalized seizures associated with occipital headaches. CT scan showed a left frontal tumor, calcified lesion with edema around it. The patient was put under Depakine and corticosteroids. The evolution is marked by the occurrence of new seizures associated with heaviness of the right arm. Brain MRI showed a left posterior peripheral frontal meningioma with intralesional bleeding and significant edema around it with mass effect on the ipsilateral lateral ventricle. The patient was operated and the tumor was removed. In postoperative there was a Broca's aphasia with right hemiplegia. Pathological anatomical examination of the surgical specimen found a cerebromeningeal Granuloma with caseous necrosis in its pseudo tumor presentation (tuberculoma). The thoraco abdominal scan did not show any other tuberculosis lesions. The patient started antituberculosis treatment with 4 drugs (HRZE) for 2 months, followed by maintenance therapy (HR).The evolution was marked by the persistence of a right hemiplegia with Broca's aphasia. The patient was brought out in a wheelchair with functional rehabilitation sessions. https://www.panafrican-med-journal.com/content/article/24/133/pdf/133.pdf cerebral tuberculomahemiplegiact scan
spellingShingle Samia Frioui
Sonia Jemni
Cerebral tuberculoma: an entity not to ignore
The Pan African Medical Journal
cerebral tuberculoma
hemiplegia
ct scan
title Cerebral tuberculoma: an entity not to ignore
title_full Cerebral tuberculoma: an entity not to ignore
title_fullStr Cerebral tuberculoma: an entity not to ignore
title_full_unstemmed Cerebral tuberculoma: an entity not to ignore
title_short Cerebral tuberculoma: an entity not to ignore
title_sort cerebral tuberculoma an entity not to ignore
topic cerebral tuberculoma
hemiplegia
ct scan
url https://www.panafrican-med-journal.com/content/article/24/133/pdf/133.pdf
work_keys_str_mv AT samiafrioui cerebraltuberculomaanentitynottoignore
AT soniajemni cerebraltuberculomaanentitynottoignore