Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021
The gold-standard treatment for ocular surface squamous neoplasia (OSSN) has traditionally been surgical excision with wide margins and a no-touch technique. However, surgery may be associated with several unfavourable sequelae, as well as significant recurrence rates if margins are positive. In rec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2021-07-01
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| Series: | BMJ Open Ophthalmology |
| Online Access: | https://bmjophth.bmj.com/content/6/1/e000842.full |
| _version_ | 1797261910183247872 |
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| author | Anat Galor Carol L Karp Mike Zein Osmel P Alvarez |
| author_facet | Anat Galor Carol L Karp Mike Zein Osmel P Alvarez |
| author_sort | Anat Galor |
| collection | DOAJ |
| description | The gold-standard treatment for ocular surface squamous neoplasia (OSSN) has traditionally been surgical excision with wide margins and a no-touch technique. However, surgery may be associated with several unfavourable sequelae, as well as significant recurrence rates if margins are positive. In recent years, topical chemotherapy with 5-fluorouracil, interferon α−2b and mitomycin C have emerged as valuable agents capable of effectively treating OSSN with varying adverse effects. These medical treatment options usually present additional costs to the patient but can allow patients to avoid surgery with fewer long-term effects. Anterior segment high-resolution optical coherence tomography is an excellent tool for diagnosing and monitoring OSSN and can be a useful aid for both surgical and medical treatments of OSSN. |
| first_indexed | 2024-04-24T23:48:43Z |
| format | Article |
| id | doaj.art-66293b7e664a46aa84473fec732d8193 |
| institution | Directory Open Access Journal |
| issn | 2397-3269 |
| language | English |
| last_indexed | 2024-04-24T23:48:43Z |
| publishDate | 2021-07-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Ophthalmology |
| spelling | doaj.art-66293b7e664a46aa84473fec732d81932024-03-15T03:40:09ZengBMJ Publishing GroupBMJ Open Ophthalmology2397-32692021-07-016110.1136/bmjophth-2021-000842Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021Anat Galor0Carol L Karp1Mike Zein2Osmel P Alvarez3Bascom Palmer Eye Institute, University of Miami, Miami, Florida, USABascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL, USABascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL, USABascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL, USAThe gold-standard treatment for ocular surface squamous neoplasia (OSSN) has traditionally been surgical excision with wide margins and a no-touch technique. However, surgery may be associated with several unfavourable sequelae, as well as significant recurrence rates if margins are positive. In recent years, topical chemotherapy with 5-fluorouracil, interferon α−2b and mitomycin C have emerged as valuable agents capable of effectively treating OSSN with varying adverse effects. These medical treatment options usually present additional costs to the patient but can allow patients to avoid surgery with fewer long-term effects. Anterior segment high-resolution optical coherence tomography is an excellent tool for diagnosing and monitoring OSSN and can be a useful aid for both surgical and medical treatments of OSSN.https://bmjophth.bmj.com/content/6/1/e000842.full |
| spellingShingle | Anat Galor Carol L Karp Mike Zein Osmel P Alvarez Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021 BMJ Open Ophthalmology |
| title | Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021 |
| title_full | Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021 |
| title_fullStr | Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021 |
| title_full_unstemmed | Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021 |
| title_short | Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021 |
| title_sort | management of ocular surface squamous neoplasia bowman club lecture 2021 |
| url | https://bmjophth.bmj.com/content/6/1/e000842.full |
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