Proteomic and phospho-proteomic profile of human platelets in basal, resting state: insights into integrin signaling.

Proteomic and phospho-proteomic profile of human platelets in basal, resting state: insights into integrin signaling.

During atherogenesis and vascular inflammation quiescent platelets are activated to increase the surface expression and ligand affinity of the integrin alphaIIbbeta3 via inside-out signaling. Diverse signals such as thrombin, ADP and epinephrine transduce signals through their respective GPCRs to ac...

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Bibliographic Details
Main Authors: Amir H Qureshi, Vineet Chaoji, Dony Maiguel, Mohd Hafeez Faridi, Constantinos J Barth, Saeed M Salem, Mudita Singhal, Darren Stoub, Bryan Krastins, Mitsunori Ogihara, Mohammed J Zaki, Vineet Gupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2762604?pdf=render

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