Evaluation of the relationship between iron status with obesity and obesity-induced inflammation in female students
Background: Anemia is the most common nutritional disorder in the world in which iron deficiency is one of its main causes. The prevalence of obesity and risk of iron deficiency anemia in these individuals is increasing. The present study examined the association between iron deficiency, dietary int...
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2018-05-01
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| Series: | Tehran University Medical Journal |
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| Online Access: | http://tumj.tums.ac.ir/browse.php?a_code=A-10-3666-39&slc_lang=en&sid=1 |
| _version_ | 1819089606797164544 |
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| author | Fatemeh Haidari Mohammad-Hossein Haghighi-Zade Gholam-Abas Kayedani Negar Karimi Birgani |
| author_facet | Fatemeh Haidari Mohammad-Hossein Haghighi-Zade Gholam-Abas Kayedani Negar Karimi Birgani |
| author_sort | Fatemeh Haidari |
| collection | DOAJ |
| description | Background: Anemia is the most common nutritional disorder in the world in which iron deficiency is one of its main causes. The prevalence of obesity and risk of iron deficiency anemia in these individuals is increasing. The present study examined the association between iron deficiency, dietary intake and obesity and obesity-induced inflammation in female students.
Methods: This descriptive cross-sectional study was conducted in Ahvaz University of Medical Sciences, Ahvaz, Iran, from May to March of 2016. A total of 170 female students were selected by stratified random sampling. Being in the age of 18-35 years, having a regular menstrual cycle, not following a specific diet and not taking any medication or dietary supplements that could affect iron status were indicators of inclusion in the study. General information and physical activity questionnaire were completed and a semi-quantitative feed frequency questionnaire was used to obtain food intake information. Anthropometric indicators including weight, height, body mass index (BMI), waist circumference and body fat were measured. Obesity was evaluated with 3 different definitions. Biochemical indices such as iron, hemoglobin, hematocrit, transferrin, total iron binding capacity (TIBC), ferritin, and hs-CRP were also measured.
Results: The dietary intake of iron and some nutrients related to iron (including energy, protein, vitamin C and calcium) showed no significant difference in dietary intake between different groups of obesity definitions. Serum iron levels and hemoglobin concentration had a significant negative correlation with BMI and hs-CRP concentrations (P=0.026 and P=0.01 respectively). The relationship between transferrin levels and total iron binding capacity with the index of waist circumference was positive and significant (P=0.040, P=0.034, respectively). Also, there was a significant positive correlation between obesity and hs-CRP levels (P=0.014). There was no significant relationship between other evaluated factors with different degrees of obesity.
Conclusion: Chronic obesity and inflammation which could be caused by obesity, can contribute to iron deficiency, regardless of dietary iron intake. |
| first_indexed | 2024-12-21T22:10:37Z |
| format | Article |
| id | doaj.art-662bb5c9dadb4acea0b3b93f06cb4e2b |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-12-21T22:10:37Z |
| publishDate | 2018-05-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-662bb5c9dadb4acea0b3b93f06cb4e2b2022-12-21T18:48:36ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222018-05-01762129134Evaluation of the relationship between iron status with obesity and obesity-induced inflammation in female studentsFatemeh Haidari0Mohammad-Hossein Haghighi-Zade1Gholam-Abas Kayedani2Negar Karimi Birgani3 Department of Nutrition, Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Department of Biostatistics and Epidemiology, Faculty of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Department of Laboratory Sciences, Faculty of Paramedical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Department of Laboratory Sciences, Faculty of Paramedical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Background: Anemia is the most common nutritional disorder in the world in which iron deficiency is one of its main causes. The prevalence of obesity and risk of iron deficiency anemia in these individuals is increasing. The present study examined the association between iron deficiency, dietary intake and obesity and obesity-induced inflammation in female students. Methods: This descriptive cross-sectional study was conducted in Ahvaz University of Medical Sciences, Ahvaz, Iran, from May to March of 2016. A total of 170 female students were selected by stratified random sampling. Being in the age of 18-35 years, having a regular menstrual cycle, not following a specific diet and not taking any medication or dietary supplements that could affect iron status were indicators of inclusion in the study. General information and physical activity questionnaire were completed and a semi-quantitative feed frequency questionnaire was used to obtain food intake information. Anthropometric indicators including weight, height, body mass index (BMI), waist circumference and body fat were measured. Obesity was evaluated with 3 different definitions. Biochemical indices such as iron, hemoglobin, hematocrit, transferrin, total iron binding capacity (TIBC), ferritin, and hs-CRP were also measured. Results: The dietary intake of iron and some nutrients related to iron (including energy, protein, vitamin C and calcium) showed no significant difference in dietary intake between different groups of obesity definitions. Serum iron levels and hemoglobin concentration had a significant negative correlation with BMI and hs-CRP concentrations (P=0.026 and P=0.01 respectively). The relationship between transferrin levels and total iron binding capacity with the index of waist circumference was positive and significant (P=0.040, P=0.034, respectively). Also, there was a significant positive correlation between obesity and hs-CRP levels (P=0.014). There was no significant relationship between other evaluated factors with different degrees of obesity. Conclusion: Chronic obesity and inflammation which could be caused by obesity, can contribute to iron deficiency, regardless of dietary iron intake.http://tumj.tums.ac.ir/browse.php?a_code=A-10-3666-39&slc_lang=en&sid=1iron-deficiency anemia overweight obesity inflammation women |
| spellingShingle | Fatemeh Haidari Mohammad-Hossein Haghighi-Zade Gholam-Abas Kayedani Negar Karimi Birgani Evaluation of the relationship between iron status with obesity and obesity-induced inflammation in female students Tehran University Medical Journal iron-deficiency anemia overweight obesity inflammation women |
| title | Evaluation of the relationship between iron status with obesity and obesity-induced inflammation in female students |
| title_full | Evaluation of the relationship between iron status with obesity and obesity-induced inflammation in female students |
| title_fullStr | Evaluation of the relationship between iron status with obesity and obesity-induced inflammation in female students |
| title_full_unstemmed | Evaluation of the relationship between iron status with obesity and obesity-induced inflammation in female students |
| title_short | Evaluation of the relationship between iron status with obesity and obesity-induced inflammation in female students |
| title_sort | evaluation of the relationship between iron status with obesity and obesity induced inflammation in female students |
| topic | iron-deficiency anemia overweight obesity inflammation women |
| url | http://tumj.tums.ac.ir/browse.php?a_code=A-10-3666-39&slc_lang=en&sid=1 |
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