Chemical profile and pancreatic lipase inhibitory activity of Sinobambusa tootsik (Sieb.) Makino leaves
Background Sinobambusa tootsik (Sieb.) Makino (S. tootsik) is one species of bamboo distributed in China, Japan and Vietnam. The chemical profile of its leaves and its potential application was unknown yet. Methods The chemical profile of S. tootsik was studied by HPLC and UPLC-DAD-QTOF-MS. The S. t...
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PeerJ Inc.
2019-09-01
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| Online Access: | https://peerj.com/articles/7765.pdf |
| _version_ | 1797420560655843328 |
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| author | Xiao-Lin Qiu Qing-Feng Zhang |
| author_facet | Xiao-Lin Qiu Qing-Feng Zhang |
| author_sort | Xiao-Lin Qiu |
| collection | DOAJ |
| description | Background Sinobambusa tootsik (Sieb.) Makino (S. tootsik) is one species of bamboo distributed in China, Japan and Vietnam. The chemical profile of its leaves and its potential application was unknown yet. Methods The chemical profile of S. tootsik was studied by HPLC and UPLC-DAD-QTOF-MS. The S. tootsik extract was prepared by extraction with 50% aqueous ethanol, followed by H103 macroporous resins adsorption and desorption processes. Pancreatic lipase inhibitory activity was determined using p-nitrophenyl palmitate as the substance, which was hydrolyzed by lipase to form coloured p-nitrophenol. Results Eighteen compounds were identified in S. tootsik. Most of them were the C-glycosylated derivatives of luteolin and apigenin, such as isoorientin, isoorientin-2″-O-rhamnoside and isovitexin. Isoorientin-2″-O-rhamnoside was the most dominant flavonoid in the sample. S. tootsik extract was prepared through resin adsorption/desorption with yield of 1.12 ± 015% and total flavonoids content of 82 ± 2 mg/g (in term of isoorientin). The extract exhibited pancreatic lipase inhibitory activity with IC50 value of 0.93 mg/mL. Conclusion The chemical profile of S. tootsik leaves was uncovered for the first time. C-glycosyl flavonoids were the main constituents in the plant. The extract exhibited pancreatic lipase inhibitory activity and may have potential for use as a food supplement for controlling obesity. |
| first_indexed | 2024-03-09T07:03:14Z |
| format | Article |
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| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T07:03:14Z |
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| spelling | doaj.art-662f013d170e4504ba853a21f6eb5f202023-12-03T09:46:35ZengPeerJ Inc.PeerJ2167-83592019-09-017e776510.7717/peerj.7765Chemical profile and pancreatic lipase inhibitory activity of Sinobambusa tootsik (Sieb.) Makino leavesXiao-Lin Qiu0Qing-Feng Zhang1College of New Energy and Environmental Engineering, Nanchang Institute of Technology, Nanchang, ChinaCollege of New Energy and Environmental Engineering, Nanchang Institute of Technology, Nanchang, ChinaBackground Sinobambusa tootsik (Sieb.) Makino (S. tootsik) is one species of bamboo distributed in China, Japan and Vietnam. The chemical profile of its leaves and its potential application was unknown yet. Methods The chemical profile of S. tootsik was studied by HPLC and UPLC-DAD-QTOF-MS. The S. tootsik extract was prepared by extraction with 50% aqueous ethanol, followed by H103 macroporous resins adsorption and desorption processes. Pancreatic lipase inhibitory activity was determined using p-nitrophenyl palmitate as the substance, which was hydrolyzed by lipase to form coloured p-nitrophenol. Results Eighteen compounds were identified in S. tootsik. Most of them were the C-glycosylated derivatives of luteolin and apigenin, such as isoorientin, isoorientin-2″-O-rhamnoside and isovitexin. Isoorientin-2″-O-rhamnoside was the most dominant flavonoid in the sample. S. tootsik extract was prepared through resin adsorption/desorption with yield of 1.12 ± 015% and total flavonoids content of 82 ± 2 mg/g (in term of isoorientin). The extract exhibited pancreatic lipase inhibitory activity with IC50 value of 0.93 mg/mL. Conclusion The chemical profile of S. tootsik leaves was uncovered for the first time. C-glycosyl flavonoids were the main constituents in the plant. The extract exhibited pancreatic lipase inhibitory activity and may have potential for use as a food supplement for controlling obesity.https://peerj.com/articles/7765.pdfSinobambusa tootsik (Sieb.) MakinoChemical profileC-glycosyl flavonoidsPancreatic lipaseInhibition |
| spellingShingle | Xiao-Lin Qiu Qing-Feng Zhang Chemical profile and pancreatic lipase inhibitory activity of Sinobambusa tootsik (Sieb.) Makino leaves PeerJ Sinobambusa tootsik (Sieb.) Makino Chemical profile C-glycosyl flavonoids Pancreatic lipase Inhibition |
| title | Chemical profile and pancreatic lipase inhibitory activity of Sinobambusa tootsik (Sieb.) Makino leaves |
| title_full | Chemical profile and pancreatic lipase inhibitory activity of Sinobambusa tootsik (Sieb.) Makino leaves |
| title_fullStr | Chemical profile and pancreatic lipase inhibitory activity of Sinobambusa tootsik (Sieb.) Makino leaves |
| title_full_unstemmed | Chemical profile and pancreatic lipase inhibitory activity of Sinobambusa tootsik (Sieb.) Makino leaves |
| title_short | Chemical profile and pancreatic lipase inhibitory activity of Sinobambusa tootsik (Sieb.) Makino leaves |
| title_sort | chemical profile and pancreatic lipase inhibitory activity of sinobambusa tootsik sieb makino leaves |
| topic | Sinobambusa tootsik (Sieb.) Makino Chemical profile C-glycosyl flavonoids Pancreatic lipase Inhibition |
| url | https://peerj.com/articles/7765.pdf |
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