Cochlear Implantation: The Volumetric Measurement of Vestibular Aqueduct and Gusher Prediction
This study aimed to validate the role of 3D segmentation in measuring the volume of the vestibular aqueduct (VAD), and the inner ear, and to study the correlation between VAD volume and VAD linear measurements at the midpoint and operculum. The correlation with other cochlear metrics was also studie...
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MDPI AG
2023-01-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/13/2/171 |
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| author | Asma Alahmadi Yassin Abdelsamad Fida Almuhawas Nezar Hamed Marzouqi Salamah Abdulrahman Alsanosi |
| author_facet | Asma Alahmadi Yassin Abdelsamad Fida Almuhawas Nezar Hamed Marzouqi Salamah Abdulrahman Alsanosi |
| author_sort | Asma Alahmadi |
| collection | DOAJ |
| description | This study aimed to validate the role of 3D segmentation in measuring the volume of the vestibular aqueduct (VAD), and the inner ear, and to study the correlation between VAD volume and VAD linear measurements at the midpoint and operculum. The correlation with other cochlear metrics was also studied. We retrospectively recruited 21 children (42 ears) diagnosed with Mondini dysplasia (MD) plus enlarged vestibular aqueduct (EVA) from 2009 to 2021 and who underwent cochlear implantation (CI). Patients’ sociodemographic data were collected, and linear cochlear metrics were measured using Otoplan. Vestibular aqueduct width and vestibular aqueduct and inner ear volumes were measured by two independent neuro-otologists using 3D segmentation software (version 4.11.20210226) and high-resolution CT. We also conducted a regression analysis to determine the association between these variables and CT VAD and inner ear volumes. Among the 33 cochlear implanted ears, 13 ears had a gusher (39.4%). Regarding CT inner ear volume, we found that gender, age, A-value, and VAD at the operculum were statistically significant (<i>p</i>-Value = 0.003, <0.001, 0.031, and 0.027, respectively) by regression analysis. Moreover, we found that Age, H value, VAD at the midpoint, and VAD at the operculum were significant predictors of CT VAD volume (<i>p</i>-Value < 0.04). Finally, gender (OR: 0.092; 95%CI: 0.009–0.982; <i>p</i>-Value = 0.048) and VAD at the midpoint (OR: 0.106; 95%CI: 0.015–0.735; <i>p</i>-Value = 0.023) were significant predictors of gusher risk. Patients’ gusher risk was significantly differentiated by gender and VAD width at the midpoint. |
| first_indexed | 2024-03-11T08:34:33Z |
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| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-11T08:34:33Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-662f8366f3204f52b0aea7156b6642cd2023-11-16T21:31:44ZengMDPI AGJournal of Personalized Medicine2075-44262023-01-0113217110.3390/jpm13020171Cochlear Implantation: The Volumetric Measurement of Vestibular Aqueduct and Gusher PredictionAsma Alahmadi0Yassin Abdelsamad1Fida Almuhawas2Nezar Hamed3Marzouqi Salamah4Abdulrahman Alsanosi5King Abdullah Ear Specialist Center (KAESC), College of Medicine, King Saud University Medical City (KSUMC), King Saud University, Riyadh 11411, Saudi ArabiaResearch Department, MED-EL GmbH, Riyadh 11411, Saudi ArabiaKing Abdullah Ear Specialist Center (KAESC), College of Medicine, King Saud University Medical City (KSUMC), King Saud University, Riyadh 11411, Saudi ArabiaKing Abdullah Ear Specialist Center (KAESC), College of Medicine, King Saud University Medical City (KSUMC), King Saud University, Riyadh 11411, Saudi ArabiaKing Abdullah Ear Specialist Center (KAESC), College of Medicine, King Saud University Medical City (KSUMC), King Saud University, Riyadh 11411, Saudi ArabiaKing Abdullah Ear Specialist Center (KAESC), College of Medicine, King Saud University Medical City (KSUMC), King Saud University, Riyadh 11411, Saudi ArabiaThis study aimed to validate the role of 3D segmentation in measuring the volume of the vestibular aqueduct (VAD), and the inner ear, and to study the correlation between VAD volume and VAD linear measurements at the midpoint and operculum. The correlation with other cochlear metrics was also studied. We retrospectively recruited 21 children (42 ears) diagnosed with Mondini dysplasia (MD) plus enlarged vestibular aqueduct (EVA) from 2009 to 2021 and who underwent cochlear implantation (CI). Patients’ sociodemographic data were collected, and linear cochlear metrics were measured using Otoplan. Vestibular aqueduct width and vestibular aqueduct and inner ear volumes were measured by two independent neuro-otologists using 3D segmentation software (version 4.11.20210226) and high-resolution CT. We also conducted a regression analysis to determine the association between these variables and CT VAD and inner ear volumes. Among the 33 cochlear implanted ears, 13 ears had a gusher (39.4%). Regarding CT inner ear volume, we found that gender, age, A-value, and VAD at the operculum were statistically significant (<i>p</i>-Value = 0.003, <0.001, 0.031, and 0.027, respectively) by regression analysis. Moreover, we found that Age, H value, VAD at the midpoint, and VAD at the operculum were significant predictors of CT VAD volume (<i>p</i>-Value < 0.04). Finally, gender (OR: 0.092; 95%CI: 0.009–0.982; <i>p</i>-Value = 0.048) and VAD at the midpoint (OR: 0.106; 95%CI: 0.015–0.735; <i>p</i>-Value = 0.023) were significant predictors of gusher risk. Patients’ gusher risk was significantly differentiated by gender and VAD width at the midpoint.https://www.mdpi.com/2075-4426/13/2/171cochlear implantationenlarged vestibular aqueductMondini dysplasiacochlear metrics |
| spellingShingle | Asma Alahmadi Yassin Abdelsamad Fida Almuhawas Nezar Hamed Marzouqi Salamah Abdulrahman Alsanosi Cochlear Implantation: The Volumetric Measurement of Vestibular Aqueduct and Gusher Prediction Journal of Personalized Medicine cochlear implantation enlarged vestibular aqueduct Mondini dysplasia cochlear metrics |
| title | Cochlear Implantation: The Volumetric Measurement of Vestibular Aqueduct and Gusher Prediction |
| title_full | Cochlear Implantation: The Volumetric Measurement of Vestibular Aqueduct and Gusher Prediction |
| title_fullStr | Cochlear Implantation: The Volumetric Measurement of Vestibular Aqueduct and Gusher Prediction |
| title_full_unstemmed | Cochlear Implantation: The Volumetric Measurement of Vestibular Aqueduct and Gusher Prediction |
| title_short | Cochlear Implantation: The Volumetric Measurement of Vestibular Aqueduct and Gusher Prediction |
| title_sort | cochlear implantation the volumetric measurement of vestibular aqueduct and gusher prediction |
| topic | cochlear implantation enlarged vestibular aqueduct Mondini dysplasia cochlear metrics |
| url | https://www.mdpi.com/2075-4426/13/2/171 |
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