Impact of microglia isolation and culture methodology on transcriptional profile and function
Abstract Background Microglial isolation and culturing methods continue to be explored to maximize cellular yield, purity, responsiveness to stimulation and similarity to in vivo microglia. This study aims to evaluate five different microglia isolation methods—three variants of microglia isolation f...
Main Authors: | Mark Mizrachi, Betty Diamond |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2024-04-01
|
Series: | Journal of Neuroinflammation |
Online Access: | https://doi.org/10.1186/s12974-024-03076-w |
Similar Items
-
Isolation, Purification, and Culture of Primary Murine Microglia Cells
by: Xuqin Chen, et al.
Published: (2013-01-01) -
Transcriptional profiling in microglia across physiological and pathological states identifies a transcriptional module associated with neurodegeneration
by: Aysegul Guvenek, et al.
Published: (2024-09-01) -
Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasound
by: Gerhard Leinenga, et al.
Published: (2023-01-01) -
The transcription factor PU.1 is critical for viability and function of human brain microglia
by: Smith, A, et al.
Published: (2013) -
The Impact of Microglia on Neurodevelopment and Brain Function in Autism
by: Yuyi Luo, et al.
Published: (2024-01-01)