IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis.
Non-alcoholic fatty liver disease is prevalent in human obesity and type 2 diabetes, and is characterized by increases in both hepatic triglyceride accumulation (denoted as steatosis) and expression of pro-inflammatory cytokines such as IL-1β. We report here that the development of hepatic steatosis...
Main Authors: | Kimberly A Negrin, Rachel J Roth Flach, Marina T DiStefano, Anouch Matevossian, Randall H Friedline, DaeYoung Jung, Jason K Kim, Michael P Czech |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4162604?pdf=render |
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