Unraveling Resistance to Immunotherapy in MSI-High Colorectal Cancer

Unraveling Resistance to Immunotherapy in MSI-High Colorectal Cancer

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths. Incidences of early CRC cases are increasing annually in high-income countries, necessitating effective treatment strategies. Immune checkpoint inhibitors (ICIs) have shown significant clin...

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Bibliographic Details
Main Authors: Ronald Heregger, Florian Huemer, Markus Steiner, Alejandra Gonzalez-Martinez, Richard Greil, Lukas Weiss
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
colorectal cancer
mismatch-repair deficiency
microsatellite instability
immune checkpoint inhibitors
immune evasion
immune escape
Online Access:https://www.mdpi.com/2072-6694/15/20/5090

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