Identification of a Diagnostic Set of Endomyocardial Biopsy microRNAs for Acute Cellular Rejection Diagnostics in Patients after Heart Transplantation Using Next-Generation Sequencing

Identification of a Diagnostic Set of Endomyocardial Biopsy microRNAs for Acute Cellular Rejection Diagnostics in Patients after Heart Transplantation Using Next-Generation Sequencing

Introduction:<b> </b>Acute cellular rejection (ACR) of heart allografts represents the most common reason for graft failure. Endomyocardial biopsies (EMB) are still subject to substantial interobserver variability. Novel biomarkers enabling precise ACR diagnostics may decrease interobser...

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Bibliographic Details
Main Authors: Tereza Nováková, Táňa Macháčková, Jan Novák, Petr Hude, Július Godava, Víta Žampachová, Jan Oppelt, Filip Zlámal, Petr Němec, Helena Bedáňová, Ondřej Slabý, Julie Bienertová-Vašků, Lenka Špinarová, Jan Krejčí
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
microrna
endomyocardial biopsy
heart transplantation
acute cellular rejection
diagnostics
Online Access:https://www.mdpi.com/2073-4409/8/11/1400

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