Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicity
Gaining a better understanding of autoprotection against drug-induced liver injury (DILI) may provide new strategies for its prevention and therapy. However, little is known about the underlying mechanisms of this phenomenon. We used single-cell RNA sequencing to characterize the dynamics and functi...
Main Authors: | Lingqi Yu, Jun Yan, Yingqi Zhan, Anyao Li, Lidan Zhu, Jingyang Qian, Fanfan Zhou, Xiaoyan Lu, Xiaohui Fan |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-08-01
|
Series: | Journal of Pharmaceutical Analysis |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177923000928 |
Similar Items
-
Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice
by: Supachaya Sriphoosanaphan, et al.
Published: (2023-05-01) -
Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity
by: Benjamin L. Prather, et al.
Published: (2023-01-01) -
Ecto-Nucleotide Triphosphate Diphosphohydrolase-2 (NTPDase2) Deletion Increases Acetaminophen-Induced Hepatotoxicity
by: Linda Feldbrügge, et al.
Published: (2020-08-01) -
CXCL5 Promotes Acetaminophen-Induced Hepatotoxicity by Activating Kupffer Cells
by: Kexin Qiu, et al.
Published: (2023-07-01) -
Autophagy, a novel player in acetaminophen (APAP)-induced hepatotoxicity
by: Hui Ye, et al.
Published: (2022-12-01)