Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR Imaging
Chemotherapy-induced liver injury has been found to be quite common in cancer patients undergoing chemotherapy. Being aware of chemotherapy-induced hepatotoxicity is important for avoiding errors in detecting liver metastases and for defining the most appropriate clinical management strategy. MRI im...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/4/867 |
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| author | Francescamaria Donati Dania Cioni Salvatore Guarino Maria Letizia Mazzeo Emanuele Neri Piero Boraschi |
| author_facet | Francescamaria Donati Dania Cioni Salvatore Guarino Maria Letizia Mazzeo Emanuele Neri Piero Boraschi |
| author_sort | Francescamaria Donati |
| collection | DOAJ |
| description | Chemotherapy-induced liver injury has been found to be quite common in cancer patients undergoing chemotherapy. Being aware of chemotherapy-induced hepatotoxicity is important for avoiding errors in detecting liver metastases and for defining the most appropriate clinical management strategy. MRI imaging has proven to be a useful troubleshooting tool that helps overcome false negatives in tumor response imaging after chemotherapy due to liver parenchyma changes. The purpose of this review is, therefore, to describe the characteristics of magnetic resonance imaging of the broad spectrum of liver damage induced by systemic chemotherapeutic agents in order to avoid misdiagnoses of liver metastases and disease progression and to define the most appropriate clinical management strategy. |
| first_indexed | 2024-03-09T10:57:16Z |
| format | Article |
| id | doaj.art-663f74c803334ea5ba59d16442acb1e1 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T10:57:16Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-663f74c803334ea5ba59d16442acb1e12023-12-01T01:32:03ZengMDPI AGDiagnostics2075-44182022-03-0112486710.3390/diagnostics12040867Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR ImagingFrancescamaria Donati0Dania Cioni1Salvatore Guarino2Maria Letizia Mazzeo3Emanuele Neri4Piero Boraschi5Department of Diagnostic, Interventional Radiology and Nuclear Medicine, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, ItalyAcademic Radiology, Department of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, ItalyDepartment of Radiology, Monaldi Hospital, AORN dei Colli, Str. Vicinale Reggente 66/82, 80131 Naples, ItalyAcademic Radiology, Department of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, ItalyAcademic Radiology, Department of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, ItalyDepartment of Diagnostic, Interventional Radiology and Nuclear Medicine, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, ItalyChemotherapy-induced liver injury has been found to be quite common in cancer patients undergoing chemotherapy. Being aware of chemotherapy-induced hepatotoxicity is important for avoiding errors in detecting liver metastases and for defining the most appropriate clinical management strategy. MRI imaging has proven to be a useful troubleshooting tool that helps overcome false negatives in tumor response imaging after chemotherapy due to liver parenchyma changes. The purpose of this review is, therefore, to describe the characteristics of magnetic resonance imaging of the broad spectrum of liver damage induced by systemic chemotherapeutic agents in order to avoid misdiagnoses of liver metastases and disease progression and to define the most appropriate clinical management strategy.https://www.mdpi.com/2075-4418/12/4/867chemotherapy-associated steatohepatitishepatic damagepeliosisnodular hyperplasiasinusoidal obstruction syndromemagnetic resonance imaging |
| spellingShingle | Francescamaria Donati Dania Cioni Salvatore Guarino Maria Letizia Mazzeo Emanuele Neri Piero Boraschi Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR Imaging Diagnostics chemotherapy-associated steatohepatitis hepatic damage peliosis nodular hyperplasia sinusoidal obstruction syndrome magnetic resonance imaging |
| title | Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR Imaging |
| title_full | Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR Imaging |
| title_fullStr | Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR Imaging |
| title_full_unstemmed | Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR Imaging |
| title_short | Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR Imaging |
| title_sort | chemotherapy induced liver injury in patients with colorectal liver metastases findings from mr imaging |
| topic | chemotherapy-associated steatohepatitis hepatic damage peliosis nodular hyperplasia sinusoidal obstruction syndrome magnetic resonance imaging |
| url | https://www.mdpi.com/2075-4418/12/4/867 |
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