Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury: Impact on Myocardial Integrity

Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury: Impact on Myocardial Integrity

Cardiac dysfunction (CD) importantly contributes to mortality in trauma patients, who survive their initial injuries following successful hemostatic resuscitation. This poor outcome has been correlated with elevated biomarkers of myocardial injury, but the pathophysiology triggering this CD remains...

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Bibliographic Details
Main Authors: Johanna Wall, Sriveena Naganathar, Banjerd Praditsuktavorn, Oscar F. Bugg, Simon McArthur, Christoph Thiemermann, Jordi L. Tremoleda, Karim Brohi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Immunology
Subjects:
trauma
cardiac dysfunction
myocardial damage
haemorrhagic injury
murine models
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02774/full

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