Association between maternal dystocia and both the oxidant/antioxidant biomarkers and blood lactate in parturient Egyptian buffaloes (Bubalus bubalis)
Dystocia is a critical obstetrical problem in farm animals and is classified into maternal or fetal dystocia. The maternal causes of dystocia include different causes such as uterine torsion (UT), failure of cervical dilation (FCD), and uterine inertia (UI). Maternal dystocia induces massive oxida...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
South Valley University
2022-10-01
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| Series: | SVU-International Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | https://svu.journals.ekb.eg/article_265437.html |
| Summary: | Dystocia is a critical obstetrical problem in farm animals and is classified into maternal or fetal
dystocia. The maternal causes of dystocia include different causes such as uterine torsion (UT), failure
of cervical dilation (FCD), and uterine inertia (UI). Maternal dystocia induces massive oxidative
stress due to increased production of free radicals with high levels of malondialdehyde (MDA). Little
information is available on oxidants and antioxidant biomarkers and blood lactate (bLac) in parturient
buffaloes with maternal dystocia. The current research aimed to clarify different causes of maternal
dystocia in buffaloes and the association between the oxidative stress of parturient buffaloes and
different types of maternal dystocia. Thirty-five parturient buffaloes were included in this study.
Parturient buffaloes included normal parturition (NP; n=7), UT (n=23), FCD (n=4), and UI (n=1).
Ten-ml blood samples were collected via jugular vein puncture into two tubes; plain vacutainer tubes
for separation of serum to measure bLac and heparin coated vacutainer tube for separation of plasma
for determination of MDA, glutathione peroxidase (GPx), and total antioxidant capacity (TAC). The
results revealed that the major cause of maternal dystocia in the included buffaloes was UT. The UT
was commonly post-cervical, clockwise, and > 180°. UT negatively affected both dam survival and
calf viability. In addition, evaluation of oxidants and antioxidants biomarkers indicated that maternal
dystocia causes more oxidative stress added to physiological stress of calving. This study found that,
4-days post-treatment period was not sufficient to resume antioxidant defense mechanism in UT
buffaloes as no significant changes had been detected throughout the sampling period after treatment
of UT. Moreover, evaluation of both GPx and bLac indicated their possible detection as indicators
for prognosis of UT cases, where the concentration of GPx was significantly lower and the
concentration of bLac was significantly higher in dead/culled buffaloes with UT. |
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| ISSN: | 2535-1826 2535-1877 |