Repurposing Disulfiram (Tetraethylthiuram Disulfide) as a Potential Drug Candidate against <i>Borrelia burgdorferi</i> In Vitro and In Vivo

Repurposing Disulfiram (Tetraethylthiuram Disulfide) as a Potential Drug Candidate against <i>Borrelia burgdorferi</i> In Vitro and In Vivo

Lyme disease caused by the <i>Borrelia burgdorferi</i> (<i>Bb or B. burgdorferi</i>) is the most common vector-borne, multi-systemic disease in the USA. Although most Lyme disease patients can be cured with a course of the first line of antibiotic treatment, some patients are...

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Bibliographic Details
Main Authors: Hari-Hara S. K. Potula, Jahanbanoo Shahryari, Mohammed Inayathullah, Andrey Victorovich Malkovskiy, Kwang-Min Kim, Jayakumar Rajadas
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Antibiotics
Subjects:
lyme disease
<i>Borrelia burgdorferi</i>
antimicrobial activity
disulfiram
lyme carditis
Online Access:https://www.mdpi.com/2079-6382/9/9/633

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