Roles of LncRNAs in Viral Infections
Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections. Accumulating research indicates that lncRNAs are...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-05-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fcimb.2017.00205/full |
| _version_ | 1818941750312435712 |
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| author | Weiwei Liu Chan Ding |
| author_facet | Weiwei Liu Chan Ding |
| author_sort | Weiwei Liu |
| collection | DOAJ |
| description | Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections. Accumulating research indicates that lncRNAs are important in the development and progression of infectious diseases. LncRNAs are not only involved in anti-viral responses, but in many different virus-host interactions, some of which may be beneficial to the virus. Here we review the current knowledge regarding host and viral lncRNAs and their roles in viral infections. In addition, the potential of using lncRNAs as diagnostic biomarkers is discussed. |
| first_indexed | 2024-12-20T07:00:30Z |
| format | Article |
| id | doaj.art-664c2aeb026d48488b6c250b88deb9d8 |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-12-20T07:00:30Z |
| publishDate | 2017-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-664c2aeb026d48488b6c250b88deb9d82022-12-21T19:49:12ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882017-05-01710.3389/fcimb.2017.00205265547Roles of LncRNAs in Viral InfectionsWeiwei LiuChan DingMany proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections. Accumulating research indicates that lncRNAs are important in the development and progression of infectious diseases. LncRNAs are not only involved in anti-viral responses, but in many different virus-host interactions, some of which may be beneficial to the virus. Here we review the current knowledge regarding host and viral lncRNAs and their roles in viral infections. In addition, the potential of using lncRNAs as diagnostic biomarkers is discussed.http://journal.frontiersin.org/article/10.3389/fcimb.2017.00205/fulllong non-coding RNAsvirus infectioncellular lncRNAsvirus-encoded lncRNAscell-virus interaction |
| spellingShingle | Weiwei Liu Chan Ding Roles of LncRNAs in Viral Infections Frontiers in Cellular and Infection Microbiology long non-coding RNAs virus infection cellular lncRNAs virus-encoded lncRNAs cell-virus interaction |
| title | Roles of LncRNAs in Viral Infections |
| title_full | Roles of LncRNAs in Viral Infections |
| title_fullStr | Roles of LncRNAs in Viral Infections |
| title_full_unstemmed | Roles of LncRNAs in Viral Infections |
| title_short | Roles of LncRNAs in Viral Infections |
| title_sort | roles of lncrnas in viral infections |
| topic | long non-coding RNAs virus infection cellular lncRNAs virus-encoded lncRNAs cell-virus interaction |
| url | http://journal.frontiersin.org/article/10.3389/fcimb.2017.00205/full |
| work_keys_str_mv | AT weiweiliu rolesoflncrnasinviralinfections AT chanding rolesoflncrnasinviralinfections |