Innate immune responses induced by the saponin adjuvant Matrix-M in specific pathogen free pigs
Abstract Saponin-based adjuvants have been widely used to enhance humoral and cellular immune responses in many species, but their mode of action is not fully understood. A characterization of the porcine transcriptional response to Matrix-M was performed in vitro using lymphocytes, monocytes or mon...
Main Authors: | Viktor Ahlberg, Bernt Hjertner, Per Wallgren, Stina Hellman, Karin Lövgren Bengtsson, Caroline Fossum |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
|
Series: | Veterinary Research |
Online Access: | http://link.springer.com/article/10.1186/s13567-017-0437-2 |
Similar Items
-
The adjuvant G3 promotes a Th1 polarizing innate immune response in equine PBMC
by: Stina Hellman, et al.
Published: (2018-10-01) -
Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection
by: Stina Hellman, et al.
Published: (2024-02-01) -
Biodistribution of the saponin-based adjuvant Matrix-M™ following intramuscular injection in mice
by: Cecilia Carnrot, et al.
Published: (2023-11-01) -
Natural and Synthetic Saponins as Vaccine Adjuvants
by: Pengfei Wang
Published: (2021-03-01) -
The Matrix-M™ adjuvant: A critical component of vaccines for the 21st century
by: Linda Stertman, et al.
Published: (2023-01-01)