Transplantation of committed pre-adipocytes from brown adipose tissue improves whole-body glucose homeostasis

Transplantation of committed pre-adipocytes from brown adipose tissue improves whole-body glucose homeostasis

Summary: Obesity and its co-morbidities including type 2 diabetes are increasing at epidemic rates in the U.S. and worldwide. Brown adipose tissue (BAT) is a potential therapeutic to combat obesity and type 2 diabetes. Increasing BAT mass by transplantation improves metabolic health in rodents, but...

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Bibliographic Details
Main Authors: Revati S. Dewal, Felix T. Yang, Lisa A. Baer, Pablo Vidal, Diego Hernandez-Saavedra, Nickolai P. Seculov, Adhideb Ghosh, Falko Noé, Olivia Togliatti, Lexis Hughes, Megan K. DeBari, Michael D. West, Richard Soroko, Hal Sternberg, Nafees N. Malik, Estella Puchulu-Campanella, Huabao Wang, Pearlly Yan, Christian Wolfrum, Rosalyn D. Abbott, Kristin I. Stanford
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Health sciences
Endocrinology
Natural sciences
Biological sciences
Physiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224001482

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