Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

Abstract Background Lysyl oxidase-like 4 (LOXL4) has been found to be dysregulated in several human malignancies, including hepatocellular carcinoma (HCC). However, the role of LOXL4 in HCC progression remains largely unclear. In this study, we investigated the clinical significance and biological i...

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Bibliographic Details
Main Authors: Rongkun Li, Yahui Wang, Xiaoxin Zhang, Mingxuan Feng, Jun Ma, Jun Li, Xiaomei Yang, Fang Fang, Qiang Xia, Zhigang Zhang, Mingyi Shang, Shuheng Jiang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Molecular Cancer
Subjects:
Hepatocellular carcinoma
LOXL4
Metastasis
Exosomes
Online Access:http://link.springer.com/article/10.1186/s12943-019-0948-8

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