Application of Monoclonal Antibody G250 Recognizing Carbonic Anhydrase IX in Renal Cell Carcinoma
Monoclonal antibody G250 (mAbG250) recognizes a determinant on carbonic anhydrase IX (CAIX). CAIX is expressed by virtually all renal cell carcinomas of the clear cell type (ccRCC), but expression in normal tissues is restricted. The homogeneous CAIX expression in ccRCC and excellent targeting capab...
Main Authors: | Egbert Oosterwijk, Peter F. A. Mulders, Jeannette C. Oosterwijk-Wakka, Otto C. Boerman |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-05-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/14/6/11402 |
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